Mal-Val-Ala-PAB-N(SO2Me)-Exatecan

级别和纯度:

有货

关闭

货号 (SKU)	包装规格	是否现货	价格	数量
M767873-1mg	1mg	期货

基本描述

规格或纯度	≥96%
英文名称	Mal-Val-Ala-PAB-N(SO2Me)-Exatecan
生化机理	Mal-Val-Ala-PAB-N(SO2Me)-Exatecan (Compound LE14) is a conjugate of an ADC toxin Exatecan and a linker Mal-Val-Ala-PAB-N(SO2Me). Mal-Val-Ala-PAB-N(SO2Me)-Exatecan can be used for synthesis of ADC FZ-AD005. FZ-AD005 is a delta-like ligand 3 (DLL3, KD=58.3 pM) targeting ADC, that exhibits antitumor efficacy against SCLC cancer.
储存温度	避光,-20°C储存
运输条件	超低温冰袋运输
产品介绍	Mal-Val-Ala-PAB-N(SO2Me)-Exatecan (Compound LE14) 是 ADC 毒素 Exatecan 和连接子 Mal-Val-Ala-PAB-N(SO2Me) 的偶联物。Mal-Val-Ala-PAB-N(SO2Me)-Exatecan 可用于合成 ADC FZ-AD005。FZ-AD005 是一种靶向 delta 样配体 3 (DLL3, KD=58.3 pM) 的 ADC，对 SCLC 癌症具有抗肿瘤活性。体外研究： ADC 由一种抗体组成，ADC 细胞毒素通过 ADC 接头连接到该抗体上。 Mal Val Ala PAB-N (SO2Me) - Exatecan (Compound LE14) is a conjugate of ADC toxin Exatecan and linker Mal Val Ala PAB-N (SO2Me). Mal Val-Ala-PAB-N (SO2Me) - Hexatecan can be used to synthesize ADC FZ-AD005. FZ-AD005 is an ADC targeting delta like ligand 3 (DLL3, KD=58.3 pM) with anti-tumor activity against SCLC cancer. In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) In vitro studies: ADC is composed of an antibody, and ADC cytotoxin is connected to the antibody through an ADC adapter.
纯度	≥96%