| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| M408721-1ml |
1ml |
现货  |
|
| 英文别名 | Myricitrine | 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)- |
|---|---|
| 规格或纯度 | 10mM in DMSO |
| 英文名称 | Myricitrin |
| 生化机理 | 三尖杉黄酮（Myricitrin）是从三尖杉根皮中分离出来的一种黄酮类化合物，具有抗痛觉作用。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
www.aladdin-reagent.com植物来源：杨梅科杨梅属植物杨梅Myrica rubra （Lour.） Sieb. et Zucc.，树叶、皮、根的提取物；杨梅(Myrica rubra Bieb.et Zucc)是原产中国的亚热带果树之一，野生种生长史已有7000多年，人工栽培已有2000多年。我国产杨梅属( Myrica L.) 植物约5 种, 主要分布于西南至东部地区。 Information Myricitrin Myricitrin (Myricitrine), a flavonoid compound isolated from the root bark of Myrica cerifera, which exerts antinociceptive effects. Myricitrin, a flavonoid compound isolated from the root bark of Myrica cerifera, which exerts antinociceptive effect. Myricitrin produces pronounced antinociception against chemical and mechanical models of pain in rodents via preventing the protein kinase C (PKC) alpha and PKC epsilon activation by phorbol myristate acetate (PMA). Another study proves that opening of voltage- and small-conductance calcium-gated K(+) channels and reduction of calcium influx leads to the antinociceptive of myricitrin. Myricitrin also decreases H2O2-induced apoptosis in vascular endothelial cells via inhibition of p53 gene expression, activation of caspase-3 and the MAPK signaling pathway, and alteration of the patterns of pro-apoptotic and anti-apoptotic gene expression. In vivo In mice, myricitrin (i.p. 10 mg/kg or 30 mg/kg) blocks apomorphine-induced stereotypy and climbing, and increases hindlimb retraction time (HRT). cell lines：DU-145 Concentrations： Incubation Time： Powder Purity:≥99% |
| EC号 | 241-856-7 |
|---|---|
| Isomeric SMILES | C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(C(=C4)O)O)O)O)O)O |
| 分子量 | 464.38 |
| Reaxy-Rn | 25132980 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25132980&ln= |
| 比旋光度 | -149 to -154 deg(C=0.5、MeOH) |
|---|---|
| 熔点 | 197°C |
| WGK Germany | 3 |
|---|
| 1. Ying Li, Haiming Hu, Huabing Yang, Aizhen Lin, Hui Xia, Xue Cheng, Mingwang Kong, Hongtao Liu. (2022) Vine Tea (Ampelopsis grossedentata) Extract Attenuates CCl4-Induced Liver Injury by Restoring Gut Microbiota Dysbiosis in Mice. MOLECULAR NUTRITION & FOOD RESEARCH, 66 (9): (2100892). [PMID:35188709] [10.1002/mnfr.202100892] |
| 2. Yilong Liu, Xianan Zhang, Liuhuan Zhan, Chang Xu, Linxiao Sun, Huamin Jiang, Chongde Sun, Xian Li. (2020) LC-Q-TOF-MS Characterization of Polyphenols from White Bayberry Fruit and Its Antidiabetic Effect in KK-Ay Mice. ACS Omega, 5 (28): (17839–17849). [PMID:32715269] [10.1021/acsomega.0c02759] |
| 3. Yu-Mei Zhao, Lv-Huan Wang, Si-Fan Luo, Qi-Qin Wang, Ruin Moaddel, Ting-Ting Zhang, Zheng-Jin Jiang. (2018) Magnetic beads-based neuraminidase enzyme microreactor as a drug discovery tool for screening inhibitors from compound libraries and fishing ligands from natural products. JOURNAL OF CHROMATOGRAPHY A, 1568 (123). [PMID:30005943] [10.1016/j.chroma.2018.07.031] |
| 4. Yang Huang, Ying Feng, Guangyun Tang, Minyi Li, Tingting Zhang, Marianne Fillet, Jacques Crommen, Zhengjin Jiang. (2017) Development and validation of a fast SFC method for the analysis of flavonoids in plant extracts. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 140 (384). [PMID:28347593] [10.1016/j.jpba.2017.03.012] |
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