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基本描述
| 英文名称 | Mutant IDH1/NAMPT-IN-1 |
|---|---|
| 产品介绍 |
Mutant IDH1/NAMPT-IN-1 (Compound 23h) is a dual inhibitor of mutant isocitrate dehydrogenase 1 (mutant IDH1 ) ( IC 50 =14.93 nM) and nicotinamide phosphoribosyltransferase ( NAMPT ) ( IC 50 =12.56 nM). Mutant IDH1/NAMPT-IN-1 can induce apoptosis. Mutant IDH1/NAMPT-IN-1 crosses the blood-brain barrier effectively. |
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