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花生四烯酸甲酯

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
M140847-50mg
50mg 现货 Stock Image
M140847-250mg
250mg 现货 Stock Image
M140847-1g
1g 现货 Stock Image
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Other Lipid (134)

基本描述

别名 全顺式-5,8,11,14-二十碳四烯酸甲酯
英文别名 (5Z,8Z,11Z,14Z)-icosatetraenoate methyl ester | AKOS000201174 | cis-5,8,11,14-Eicosatetraenoic acidmethyl ester | (5Z,8Z,11Z,14Z)-Methylicosa-5,8,11,14-tetraenoate | 5,8,11,14-Eicosatetraenoic acid, methyl ester, (all-Z)- (8CI); Arachidonic acid, methyl e
规格或纯度 Moligand™, ≥90%(GC)
英文名称 Methyl arachidonate
生化机理 与大多数不饱和脂肪酸甲酯不同,花生四烯酸甲酯在 5 50 μM 时是蛋白激酶 C 的强效激活剂。在有效浓度范围的低端,因环加氧酶产物而产生作用,而脂氧合酶产物在较高浓度下介导效果。
储存温度 -20°C储存
运输条件 超低温冰袋运输
产品介绍

Arachidonic Acid methyl ester is the keystone essential fatty acid at the origin of the arachidonic acid cascade. It is converted by cyclooxygenase, lipoxygenase, and epoxygenase enzymes into more than one hundred fifty different potent primary autacoid metabolites in species ranging from fungi to plants to mammals. Arachidonic acid is stored in tissue phospholipids in esterified form, where it comprises a small but critically controlled percentage of the polyunsaturated fatty acid pool. Arachidonic acid content is frequently measured by the saponification of the lipid fraction followed by methyl esterification and gas chromatographic analysis of the resulting FAME (fatty acid methyl ester) compounds. Arachidonic acid methyl ester can also be incorporated into dietary regimens or fed to cultured cells as a source of exogenous arachidonate.The keystone essential fatty acid at the origin of the arachidonic acid cascade

Arachidonic Acid methyl ester is the keystone essential fatty acid at the origin of the arachidonic acid cascade. It is converted by cyclooxygenase, lipoxygenase, and epoxygenase enzymes into more than one hundred fifty different potent primary autacoid metabolites in species ranging from fungi to plants to mammals. Arachidonic acid is stored in tissue phospholipids in esterified form, where it comprises a small but critically controlled percentage of the polyunsaturated fatty acid pool. Arachidonic acid content is frequently measured by the saponification of the lipid fraction followed by methyl esterification and gas chromatographic analysis of the resulting FAME (fatty acid methyl ester) compounds. Arachidonic acid methyl ester can also be incorporated into dietary regimens or fed to cultured cells as a source of exogenous arachidonate.
The keystone essential fatty acid at the origin of the arachidonic acid cascade

纯度 ≥90%(GC)

名称和识别符

PubChem SID 504764126
IIUPAC Name methyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
INCHI 1S/C21H34O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21(22)23-2/h7-8,10-11,13-14,16-17H,3-6,9,12,15,18-20H2,1-2H3/b8-7-,11-10-,14-13-,17-16-
InChi Key OFIDNKMQBYGNIW-ZKWNWVNESA-N
Smiles CCCCCC=CCC=CCC=CCC=CCCCC(=O)OC
Isomeric SMILES CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC
分子量 318.49
Beilstein号 1714445
Reaxy-Rn 22931884
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22931884&ln=

化学和物理性质

溶解性 Soluble in heptane (10 mg/ml), ethanol, DMSO, DMF, and ethanol:PBS(pH 7.2)(1:1) (~0.5 mg/ml)
密度 0.9
敏感性 对湿度敏感
折光率 1.49
沸点 403.94 °C
分子量 318.500 g/mol
XLogP3 6.600
氢键供体数Hydrogen Bond Donor Count 0
氢键受体数Hydrogen Bond Acceptor Count 2
可旋转键计数Rotatable Bond Count 15
精确质量Exact Mass 318.256 Da
单同位素质量Monoisotopic Mass 318.256 Da
拓扑极表面积Topological Polar Surface Area 26.300 Ų
重原子数Heavy Atom Count 23
形式电荷Formal Charge 0
复杂度Complexity 375.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 4
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 4
共价键合单元计数Covalently-Bonded Unit Count 1

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批号(Lot Number) 证书类型 货号
C2526282 分析证书 M140847
C2303625 分析证书 M140847
C2303723 分析证书 M140847
C2303727 分析证书 M140847
C2303734 分析证书 M140847
C2303766 分析证书 M140847

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