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脂多糖 来源于大肠杆菌 0127:B8

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
L755723-1mg
1mg 期货 Stock Image

基本描述

规格或纯度 γ-irradiated, BioReagent, 用于细胞培养
英文名称 Lipopolysaccharides from Escherichia coli O127:B8
生化机理 脂多糖(LPS)是革兰氏阴性菌细胞壁的特征组分。LPS和它的脂质A单体通过Toll样受体4(TLR4)激活天然免疫系统细胞。作为免疫原抗原,它增强了对于可溶性抗原的免疫反应。
储存温度 2-8°C储存
运输条件 冰袋运输
产品介绍

来自Escherichia coli 0127:B8脂多糖用于:研究LPS诱导小鼠巨噬细胞存活 诱导牛PBMC分泌细胞因子 研究LPS诱导促炎环境高易感巨噬细胞细胞凋亡。进行BV2和BV2-LC3细胞自吞噬实验。激活人单核细胞,巨噬细胞和小鼠小胶质细胞诱导293T细胞穿透素-3脂多糖(LPS)是革兰氏阴性菌细胞壁的特征组分。LPS及其脂质A部分可通过能够识别常见的病原体相关分子模式(PAMP)的Toll样受体蛋白家族成员Toll样受体4(TLR4)刺激先天性免疫系统细胞。

Lipopolysaccharides from Escherichia coli 0127:B8 has been used:
  • to study the LPS-induced macrophage survival in mice
  • to elicit the secretion of cytokines by cattle PBMC
  • to study apoptosis of highly susceptible macrophage cells in a LPS-induced proinflammatory environment
  • to perform autophagy assay in BV2 and BV2-LC3 cells
  • for stimulation of human monocytes, macrophages and mouse microglia cells
  • to induce pentraxin-3 expression in 293T cells
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).

化学和物理性质

溶解性 H 2 O: 5 mg/mL, slightly hazy

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

溶液计算器