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| 规格或纯度 | γ-irradiated, BioReagent, 用于细胞培养 |
|---|---|
| 英文名称 | Lipopolysaccharides from Escherichia coli O127:B8 |
| 生化机理 | 脂多糖(LPS)是革兰氏阴性菌细胞壁的特征组分。LPS和它的脂质A单体通过Toll样受体4(TLR4)激活天然免疫系统细胞。作为免疫原抗原,它增强了对于可溶性抗原的免疫反应。 |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| 产品介绍 |
来自Escherichia coli 0127:B8脂多糖用于:研究LPS诱导小鼠巨噬细胞存活 诱导牛PBMC分泌细胞因子 研究LPS诱导促炎环境高易感巨噬细胞细胞凋亡。进行BV2和BV2-LC3细胞自吞噬实验。激活人单核细胞,巨噬细胞和小鼠小胶质细胞诱导293T细胞穿透素-3脂多糖(LPS)是革兰氏阴性菌细胞壁的特征组分。LPS及其脂质A部分可通过能够识别常见的病原体相关分子模式(PAMP)的Toll样受体蛋白家族成员Toll样受体4(TLR4)刺激先天性免疫系统细胞。 Lipopolysaccharides from Escherichia coli 0127:B8 has been used:
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs). |
| 溶解性 | H 2 O: 5 mg/mL, slightly hazy |
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