L-谷氨酰胺-(酰胺-¹⁵N)

COA

级别和纯度:

≥98 atom% 15N,≥98%

CAS编号: 59681-32-2
分子式: H₂₁₅NCO(CH₂)2CH(NH₂)CO₂H
分子量: 147.14
MDL号: MFCD00084214
PubChem编号: 15560190

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货号 (SKU)	包装规格	是否现货
L471860-50mg	50mg	现货
L471860-250mg	250mg	现货
L471860-1g	1g	现货

查看相关系列

Apoptosis (7108) Class C GPCR (399) Ferroptosis (624) GPCR/G Protein (3179) mGluR (175) 代谢物 (8911) 神经元信号传导 (3320)

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基本描述

英文别名	L-Glutamine-15N-1 \| MS-22834 \| (2S)-2-amino-5-(15N)azanyl-5-oxopentanoic acid \| L-Glutamine-amide-15N \| Acustasin-15N \| L-Glutamine-(amide-15N), 98 atom % 15N \| L-(N~5~-~15~N)Glutamine \| Aesgen 14-15N \| L-Glutamine-(amide-15N) \| DTXSID00574155 \| HY-N0390S
规格或纯度	≥98 atom% 15N,≥98%
英文名称	L-Glutamine-(amide-¹⁵N)
生化机理	L-Glutamine, a source of nitrogen, mainly contributes to the synthesis of proteins, peptides, purine, pyrimidine, nucleotides, nucleic acids and major precursor of neurotransmitter. It acts as a fuel for the proliferation of lymphocytes and macrophages of immune system, for intestinal tissue to maintain gut integrity and for insulin production. L-Glutamine is released by skeletal muscle during stress conditions.
储存温度	2-8°C储存,避光,充氩
运输条件	冰袋运输
作用类型	抑制剂
产品介绍	Description L-Glutamine is a branched chain, non-essential amino acid. It is one of the most abundant amino acid found in central nervous system (CNS), plasma and human skeletal muscle.(2) L- Glutamine is synthesized by transamination of glutamate catalyzed by glutamine synthetase.
纯度	≥98 atom% 15N,≥98%

名称和识别符

分子类型	小分子
IIUPAC Name	(2S)-2-amino-5-(15N)azanyl-5-oxopentanoic acid
INCHI	1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1/i7+1
InChi Key	ZDXPYRJPNDTMRX-QQKKVIQDSA-N
Smiles	C(CC(=O)N)C(C(=O)O)N
Isomeric SMILES	C(CC(=O)[15NH2])[C@@H](C(=O)O)N
关联CAS	56-85-9（unlabelled）
分子量	147.14
Reaxy-Rn	1723795
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1723795&ln=

化学和物理性质

敏感性	对光敏感；对湿度敏感
熔点	185 °C
分子量	147.140 g/mol
XLogP3	-3.100
氢键供体数Hydrogen Bond Donor Count	3
氢键受体数Hydrogen Bond Acceptor Count	4
可旋转键计数Rotatable Bond Count	4
精确质量Exact Mass	147.066 Da
单同位素质量Monoisotopic Mass	147.066 Da
拓扑极表面积Topological Polar Surface Area	106.000 Å²
重原子数Heavy Atom Count	10
形式电荷Formal Charge	0
复杂度Complexity	146.000
同位素原子数Isotope Atom Count	1
定义的原子立体中心计数Defined Atom Stereocenter Count	1
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

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找到3个结果

批号(Lot Number)	证书类型	货号
J2523774	分析证书	L471860
J2523760	分析证书	L471860
J2523773	分析证书	L471860

引用文献

1. Cao L, Weetall M, Trotta C, Cintron K, Ma J, Kim MJ, Furia B, Romfo C, Graci JD, Li W et al.. (2019) Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties.. Mol Cancer Ther, 18 (1): (3-16). [PMID:30352802]
2. Katarzyna Dąbrowska,Jan Albrecht,Magdalena Zielińska. (2018-07-19) Protein kinase C-mediated impairment of glutamine outward transport and SN1 transporter distribution by ammonia in mouse cortical astrocytes.. Neurochemistry international, 118 (225-232). [PMID:30017230]
3. Min Yuan, Daniel M Kremer, He Huang, Susanne B Breitkopf, Issam Ben-Sahra, Brendan D Manning, Costas A Lyssiotis, John M Asara,. (2019-01-27) Ex vivo and in vivo stable isotope labelling of central carbon metabolism and related pathways with analysis by LC-MS/MS.. Nature protocols, 14 ((2)): ( 313-330 ). [PMID:30683937]
4. Vanessa Byles,Yann Cormerais,Krystle Kalafut,Victor Barrera,James E Hughes Hallett,Shannan Ho Sui,John M Asara,Christopher M Adams,Gerta Hoxhaj,Issam Ben-Sahra,Brendan D Manning. (2021-07-26) Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin.. Molecular metabolism, 53 (101309-101309). [PMID:34303878]

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