HTH-01-091 TFA

级别和纯度:

有货

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货号 (SKU)	包装规格	是否现货	价格	数量
H659342-5mg	5mg	期货

查看相关系列

Apoptosis (7108) CDK (251) Cell Cycle (7376) Cell Cycle/DNA Damage (2603) DYRK (39) Extrinsic Pathway (1228) GSK-3 (105) JAK/STAT Signaling (508) MELK (11) MTOR (146) Non-receptor Tyrosine Kinase (1390) PI3K/Akt/mTOR (764) Pim (31) Protein Tyrosine Kinase/RTK (1319) RIP kinase (65) Stem Cell/Wnt (1018)

基本描述

别名	HTH-01-091 三氟乙酸
规格或纯度	≥98%
英文名称	HTH-01-091 TFA
储存温度	-20°C储存
运输条件	超低温冰袋运输
作用类型	抑制剂
产品介绍	HTH-01-091 TFA is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor, with an IC 50 of 10.5 nM. HTH-01-091 TFA also inhibits PIM1/2/3 , RIPK2 , DYRK3 , smMLCK and CLK2 . HTH-01-091 TFA can be uesd for breast cancer research. Appearance:Solid IC50& Target:IC50: 10.5 nM (MELK), 41.8 nM (DYRK3), 42.5 nM (RIPK2), 60.6 nM (PIM1), 108.6 nM (smMLCK), 632 nM (mTOR), 962 nM (PIK3CA), 1230 nM (CDK7), 1740 nM (GSK3A) In Vitro:HTH-01-091 (1 μM) TFA selectively inhibits 4% of the kinases over 90%. HTH-01-091 (0-10 μM, 1 h) TFA is cell permeable and causes MELK degradation. HTH-01-091 (0-10 μM, 3 day) TFA exhibits minor antiproliferative effects in breast cancer cells. Biological Activity:HTH-01-091 TFA is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor, with an IC 50 of 10.5 nM. HTH-01-091 TFA also inhibits PIM1/2/3 , RIPK2 , DYRK3 , smMLCK and CLK2 . HTH-01-091 TFA can be uesd for breast cancer research.
纯度	≥98%