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主题:DNA

按主题分类的文章 "DNA"

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  1. DNA Damage and Repair The formation of mutations and the development of cancer both involve damage to a cell's DNA. DNA in human cells is damaged thousands to millions of times a day by both external (exogenous) and internal metabolism (endogenous). Changes in a cell's genome can lead to errors in the transcription ...
  2. DNA损伤和修复 细胞DNA的损伤与突变和癌症的发生有关。人类细胞中的DNA每天要经历数千到数百万次的破坏事件,这些事件是由外部(外源性)和内部代谢(内源性)过程产生的。细胞基因组的改变会在DNA转录中产生错误,并随后翻译成信号传递和细胞功能所必需的蛋白质。如果突变在有丝分裂之前没有修复,基因组突变也可以传递到子代细胞。一旦细胞失去有效修复受损DNA的能力,就有三种可能的反应 ...
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