按主题分类的文章 "LRRK2 Inhibitors"

1. LRRK2 Inhibitors
   发布于 2025年8月20日

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   Leucine-rich repeat kinase 2 (LRRK2) is a protein localized in both the cytoplasm and the outer membrane of mitochondria. Gain-of-function mutations in LRRK2 have been linked to an elevated risk of Crohn’s disease as well as Parkinson’s disease. Parkinson’s disease models indicate that such ...