FTO-IN-8

级别和纯度:

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货号 (SKU)	包装规格	是否现货
F651215-5mg	5mg	期货
F651215-10mg	10mg	期货
F651215-25mg	25mg	期货
F651215-50mg	50mg	期货
F651215-100mg	100mg	期货

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基本描述

规格或纯度	≥98%
英文名称	FTO-IN-8
生化机理	FTO-IN-8（FTO-43）是一种 N6-甲基腺苷脱甲基酶（FTO）（脂肪量和肥胖相关蛋白）抑制剂，IC50 值为 5.5 μM。FTO-IN-8 具有抗癌细胞增殖活性。
储存温度	-20°C储存
运输条件	超低温冰袋运输
作用类型	抑制剂
产品介绍	FTO-IN-8 (FTO-43) is a N6-methyladenosine demethylase ( FTO ) (fat mass- and obesity-associated protein) inhibitor with the IC 50 value of 5.5 μM. FTO-IN-8 has anti-cancer cell proliferative activity. In Vitro FTO-IN-8 (FTO-43) (0-50 μM, 24-72 h) inhibits the proliferation of cancer cells with no cytotoxicity to normal colonic cells. FTO-IN-8 (FTO-43) can increase m 6 A and m 6 A m levels and inhibits Wnt/PI3K-Akt signaling in gastric cancer AGS cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: AGS, SNU16, and KATOIII cell lines Concentration: 0-50 μM Incubation Time: 24, 48, 72 hours Result: Inhibited the growth of SNU16, KATOIII and AGS with the EC 50 values of 17.7 μM, 35.9 μM and 20.3 μM, respectively. Form:Oil
纯度	≥98%