| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| D656435-1ml |
1ml |
期货  |
|
| 别名 | 抗凝素 |
|---|---|
| 规格或纯度 | 10mM in DMSO |
| 英文名称 | Diaplasinin |
| 生化机理 | Diaplasinin（PAI-749）是一种纤溶酶原激活物抑制剂-1（PAI-1）抑制剂，IC50 为 295u2003nm。抗血栓功效。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 抑制剂 |
| 产品介绍 |
Diaplasinin (PAI-749) is a plasminogen activator inhibitor-1 ( PAI-1 ) inhibitor with IC 50 of 295 nm. Antithrombotic efficacy. In Vitro PAI-749 is a potent and selective synthetic antagonist of plasminogen activator inhibitor 1 (PAI-1) that preserved tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA) activities in the presence of PAI-1 (IC 50 values, 157 and 87 nM, respectively). PAI-749 quenches the fluorescence (Fl) of fluorophore-tagged PAI-1 (PAI-NBD119) with the apparent K d of 254 nM) and the IC 50 of 140 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Isomeric SMILES | CCCCCC1=C(N(C2=CC=CC=C21)CC3=CC=CC=C3)C4=CC5=C(C=C4)C=C(C=C5)OCC6=NNN=N6 |
|---|---|
| PubChem CID | 6450820 |
| 分子量 | 501.62 |
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