| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| D463289-5mg |
5mg |
现货  |
|
| 别名 | 因子 B | 苯钴胺 |
|---|---|
| 英文别名 | Factor B | Cobinamide dicyanide | Etiocobalamin |
| 规格或纯度 | ≥93% |
| 英文名称 | Dicyanocobinamide |
| 生化机理 | 二氰基钴啉醇酰胺（Cbi）可用作可溶性鸟苷酸环化酶（sGC）辅助激活因子，并以N末端调节区为靶点。该作用类似于佛司可林对腺苷酸环化酶的作用。二氰基钴啉醇酰胺可提高大鼠细胞内环单磷酸鸟苷（cGMP）的水平，并在大鼠中表现出血管舒张活性。它可与多种钴胺素一起用于HIV-1整合酶和一氧化氮合酶抑制的研究。 |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
二氰基钴啉醇酰胺也称为因子b，是辅酶B12的前体。它具有咕啉环结构，钴（Co）原子的六个配位点中有四个是吡咯氮原子。 应用 用于测定内因子制剂中的非内因子（R蛋白）。二氰基钴啉醇酰胺已被用于维生素B12结合蛋白（BtuF）的结晶。它还被用于BtuCD-BtuF相互作用的脱稳。 Dicyanocobinamide, also known as factor b is a coenzyme B12 precursor. It has a corrin ring structure with four of the six coordination sites of the cobalt (Co) atom being the pyrrole nitrogen atoms.Dicyanocobinamide has been used for the crystallization of vitamin B12-binding protein (BtuF). It has also been used for the destabilization of BtuCD-BtuF Interaction.For use in determining non-intrinsic factor (R protein) in intrinsic factor preparations. |
| 纯度 | ≥93% |
| PubChem SID | 504764208 |
|---|---|
| IIUPAC Name | cobalt;3-[(1R,2S,3S,5Z,7S,8S,10Z,13S,15Z,17R,18R)-2,7,18-tris(2-amino-2-oxoethyl)-3,13-bis(3-amino-3-oxopropyl)-17-[3-(2-hydroxypropylamino)-3-oxopropyl]-1,2,5,7,12,12,15,17-octamethyl-8,13,18,19-tetrahydro-3H-corrin-24-id-8-yl]propanamide;dicyanide |
| INCHI | 1S/C48H73N11O8.2CN.Co/c1-23(60)22-55-38(67)16-17-45(6)29(18-35(52)64)43-48(9)47(8,21-37(54)66)28(12-15-34(51)63)40(59-48)25(3)42-46(7,20-36(53)65)26(10-13-32(49)61)30(56-42)19-31-44(4,5)27(11-14-33(50)62)39(57-31)24(2)41(45)58-43;2*1-2;/h19,23,26-29,43,60H,10-18,20-22H2,1-9H3,(H14,49,50,51,52,53,54,55,56,57,58,59,61,62,63,64,65,66,67);;;/q;2*-1;/p-1/t23?,26-,27-,28-,29+,43?,45-,46+,47+,48+;;;/m1.../s1 |
| InChi Key | NWXVHVXSDZHCFS-TWXWJCICSA-M |
| Smiles | CC1=C2C(C(C([N-]2)C3(C(C(C(=N3)C(=C4C(C(C(=N4)C=C5C(C(C1=N5)CCC(=O)N)(C)C)CCC(=O)N)(C)CC(=O)N)C)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)(C)CCC(=O)NCC(C)O.[C-]#N.[C-]#N.[Co] |
| Isomeric SMILES | C/C/1=C/2\[C@@]([C@@H](C(=N2)/C=C\3/C([C@@H](C(=N3)/C(=C\4/[C@]([C@H](C([N-]4)[C@]5([C@@]([C@@H](C1=N5)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)(C)CCC(=O)NCC(C)O)/C)CCC(=O)N)(C)C)CCC(=O)N)(C)CC(=O)N.[C-]#N.[C-]#N.[Co] |
| PubChem CID | 6450878 |
| 分子量 | 1042.12 |
| 闪点(℉) | Not applicable |
|---|---|
| 闪点(℃) | Not applicable |
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