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DOTAP转染试剂

用于转染DNA,RNA和YAC的阳离子脂质制剂。
    级别和纯度:
  • 1 mg/ml in MES-buffered saline
有货

库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
D353304-400μl
400μl 现货 Stock Image
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脂质代谢 (4331)

基本描述

英文别名 DOTAP | 18:1 TAP (DOTAP, MS Salt), 1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt), chloroform | N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium methyl sulfate | DOTAP Liposomal Transfection Reagent, N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-t
规格或纯度 1 mg/ml in MES-buffered saline
英文名称 DOTAP Transfection Reagent
储存温度 2-8°C储存
运输条件 冰袋运输
产品介绍

DOTAP Transfection Reagent是阳离子脂质DOTAP的脂质体制剂。DOTAP Transfection Reagent不仅可用于DNA和RNA转染,还可以用于酵母人工染色体(YAC),带有或不带有血清。通过DOTAP Transfection Reagent进行的这种转染是在真核细胞之间进行瞬时或稳定的基因表达。DOTAP Transfection Reagent也适用于其他带负电荷的分子,包括寡核苷酸和谷氨酸。

DOTAP Transfection Reagent is a liposomal formulation of the cationic lipid DOTAP. DOTAP Transfection Reagent is used not only for DNA and RNA transfection, but yeast artificial chromosomes (YAC) as well, with or without serum. This transfection via DOTAP Transfection Reagent is between eukaryotic cells in iehter transient or stable gene expression. DOTAP Transfection Reagent is also suitable for other negatively charged molecules, including oligonucleotidees and glutamic acid.

名称和识别符

IIUPAC Name 2,3-bis[[(Z)-octadec-9-enoyl]oxy]propyl-trimethylazanium;methyl sulfate
INCHI 1S/C42H80NO4.CH4O4S/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-5-6(2,3)4/h20-23,40H,6-19,24-39H2,1-5H3;1H3,(H,2,3,4)/q+1;/p-1/b22-20-,23-21-;
InChi Key RSMRWWHFJMENJH-LQDDAWAPSA-M
Smiles CCCCCCCCC=CCCCCCCCC(=O)OCC(C[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC.COS(=O)(=O)[O-]
Isomeric SMILES CCCCCCCC/C=C\CCCCCCCC(=O)OCC(C[N+](C)(C)C)OC(=O)CCCCCCC/C=C\CCCCCCCC.COS(=O)(=O)[O-]
分子量 774.19
Reaxy-Rn 34197390
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=34197390&ln=

化学和物理性质

沸点 100 °C
熔点 -5 °C
分子量 774.200 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count 0
氢键受体数Hydrogen Bond Acceptor Count 8
可旋转键计数Rotatable Bond Count 37
精确质量Exact Mass 773.584 Da
单同位素质量Monoisotopic Mass 773.584 Da
拓扑极表面积Topological Polar Surface Area 127.000 Ų
重原子数Heavy Atom Count 53
形式电荷Formal Charge 0
复杂度Complexity 845.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 1
定义的键立体中心计数Defined Bond Stereocenter Count 2
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 2
共价键合单元计数Covalently-Bonded Unit Count 2

安全和危险性(GHS)

预防措施声明

P264: 处理后要彻底洗手。

WGK Germany 3

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

此产品的引用文献

引用文献

1. Yandong Xie, Xueying Lu, Zhen Wang, Mingxi Liu, Liang Liu, Ran Wang, Kun Yang, Hong Xiao, Jianyong Li, Xianglong Tang, Hongyi Liu.  (2022)  A hypoxia-dissociable siRNA nanoplatform for synergistically enhanced chemo-radiotherapy of glioblastoma.  Biomaterials Science,  10  (23): (6791-6803).  [PMID:36314541] [10.1039/D2BM01145J]

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