| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| D163638-100mg |
100mg |
现货  |
| |
| D163638-500mg |
500mg |
现货 |
|
| 规格或纯度 | MW 5000 Da |
|---|---|
| 英文名称 | DSPE PEG, mPEG-DSPE |
| 储存温度 | 避光,-20°C储存,充氩 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjμgated Polyethylene Glycol, DSPE PEG is a phospholipid PEG conjμgate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drμg delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drμgs. These materials can also be used for targeted drμg delivery by modifying their surfaces with targeting ligands such as antibodies, peptides. 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated Polyethylene Glycol, DSPE PEG is a phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides. |
| IIUPAC Name | sodium;[(2R)-2,3-di(octadecanoyloxy)propyl] 2-(2-methoxyethoxycarbonylamino)ethyl phosphate |
|---|---|
| INCHI | 1S/C45H88NO11P.Na/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-43(47)54-40-42(41-56-58(50,51)55-37-36-46-45(49)53-39-38-52-3)57-44(48)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2;/h42H,4-41H2,1-3H3,(H,46,49)(H,50,51);/q;+1/p-1/t42-;/m1./s1 |
| InChi Key | SRLOHQKOADWDBV-NRONOFSHSA-M |
| Smiles | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCCNC(=O)OCCOC)OC(=O)CCCCCCCCCCCCCCCCC.[Na+] |
| Isomeric SMILES | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCCNC(=O)OCCOC)OC(=O)CCCCCCCCCCCCCCCCC.[Na+] |
| Reaxy-Rn | 60733557 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=60733557&ln= |
| 溶解性 | Off-white/white solid or semi-solid depends on molecule weight;Soluble in warm water and chloroform; |
|---|---|
| 敏感性 | 对光线、湿度、热敏感 |
| 分子量 | 872.100 g/mol |
| XLogP3 | |
| 氢键供体数Hydrogen Bond Donor Count | 1 |
| 氢键受体数Hydrogen Bond Acceptor Count | 11 |
| 可旋转键计数Rotatable Bond Count | 48 |
| 精确质量Exact Mass | 871.591 Da |
| 单同位素质量Monoisotopic Mass | 871.591 Da |
| 拓扑极表面积Topological Polar Surface Area | 159.000 Ų |
| 重原子数Heavy Atom Count | 59 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 994.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 1 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 2 |
| 信号词 | Warning |
|---|---|
| 危险声明 |
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P301+P312: 如误吞咽：如感觉不适，呼叫急救中心/医生。 |
¥119.90
¥122.90
| 1. Zhenhu Guo, Xiaohan Gao, Jingsong Lu, Ying Li, Zeping Jin, Abdul Fahad, Neema Ufurahi Pambe, Hirotaka Ejima, Xiaodan Sun, Xiumei Wang, Wensheng Xie, Guifeng Zhang, Lingyun Zhao. (2024) Apoptosis and Paraptosis Induced by Disulfiram-Loaded Ca2+/Cu2+ Dual-Ions Nano Trap for Breast Cancer Treatment. ACS Nano, 9 (18): (6975–6989). [10.1021/acsnano.3c10173] |
| 2. Beibei Zhang, Hao Liu, Yifei Wang, Yong Zhang. (2024) ROS-Responsive and Self-Catalytic Nanocarriers for a Combination of Chemotherapy and Reinforced Ferroptosis against Breast Cancer. ACS Biomaterials Science & Engineering, 10 (10): (6352-6362). [PMID:39262329] [10.1021/acsbiomaterials.4c01233] |
首页
400-620-6333
1篇引用文献 
E2528424