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二亚乙基三胺五乙酸二酐(DTPA)

9篇引用文献 COA COA
    级别和纯度:
  • ≥98%
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
D106364-1g
 1g 现货 Stock Image
D106364-5g
 5g 期货 Stock Image
D106364-25g
 25g 现货 Stock Image
D106364-100g
 100g 现货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
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羧酸 (2181) 聚合物/高分子试剂 (683)
main product photo

基本描述

别名 DTPA 二酐
英文别名 NSC-125674 | NSC379317 | NSC-379317 | Uric acid, >=99%, crystalline | Glycine, N,N-bis(2-(2,6-dioxo-4-morpholinyl)ethyl)- | DTPA-Anhydride | Diethylenetriaminepentaacetic dianhydride | N,N-Bis[2-(2,6-dioxomorpholino)ethyl]glycine | Glycine, N,N-bis[2-(2,6
规格或纯度 ≥98%
英文名称 Diethylenetriaminepentaacetic acid dianhydride
应用 用于合成用作核磁共振成像增强剂的大环配合物和镧系络?合物。
运输条件 常规运输
产品介绍

用于合成用作核磁共振成像增强剂的大环配合物和镧系络?合物。

Employed in the synthesis of macrocyclic ligands and lanthanide complexes that are useful as MRI enhancers
纯度 ≥98%

名称和识别符

PubChem SID 504756467
IIUPAC Name 2-[bis[2-(2,6-dioxomorpholin-4-yl)ethyl]amino]acetic acid
INCHI 1S/C14H19N3O8/c18-10(19)5-15(1-3-16-6-11(20)24-12(21)7-16)2-4-17-8-13(22)25-14(23)9-17/h1-9H2,(H,18,19)
InChi Key RAZLJUXJEOEYAM-UHFFFAOYSA-N
Smiles C1C(=O)OC(=O)CN1CCN(CCN2CC(=O)OC(=O)C2)CC(=O)O
Isomeric SMILES C1C(=O)OC(=O)CN1CCN(CCN2CC(=O)OC(=O)C2)CC(=O)O
分子量 357.32
Beilstein号 1230954
Reaxy-Rn 1230954
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1230954&ln=

化学和物理性质

溶解性 可溶于甲醇
敏感性 对湿度敏感
熔点 182-184°C
分子量 357.320 g/mol
XLogP3 -3.300
氢键供体数Hydrogen Bond Donor Count 1
氢键受体数Hydrogen Bond Acceptor Count 11
可旋转键计数Rotatable Bond Count 8
精确质量Exact Mass 357.117 Da
单同位素质量Monoisotopic Mass 357.117 Da
拓扑极表面积Topological Polar Surface Area 134.000 Ų
重原子数Heavy Atom Count 25
形式电荷Formal Charge 0
复杂度Complexity 504.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS07
信号词 警告
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激
预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P264: 处理后要彻底洗手。

P271: 仅在室外或通风良好的地方使用。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P321: 特殊处理（请参阅此标签上的...）。

P302+P352: 如皮肤沾染：用水充分清洗。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P405: 密闭存放

P403+P233: 存放在通风良好的地方。保持容器密闭。

P501: 将内容物/容器处理到。。。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。

P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany 3
个人防护装备 dust mask type N95 (US),Eyeshields,Gloves

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到13个结果

批号(Lot Number) 证书类型 货号
D2319245 分析证书 D106364
D2319274 分析证书 D106364
C2517147 分析证书 D106364
D23191091 分析证书 D106364
D23191111 分析证书 D106364
K2330160 分析证书 D106364
B2505120 分析证书 D106364
J2211468 分析证书 D106364
J2228410 分析证书 D106364
J2228433 分析证书 D106364
J2228434 分析证书 D106364
J2228484 分析证书 D106364
C1807087 分析证书 D106364

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引用文献

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7. Ying-Hsia Shih,Tsai-Yueh Luo,Ping-Fang Chiang,Cheng-Jung Yao,Wuu-Jyh Lin,Cheng-Liang Peng,Ming-Jium Shieh.  (2017-04-27)  EGFR-targeted micelles containing near-infrared dye for enhanced photothermal therapy in colorectal cancer..  Journal of controlled release : official journal of the Controlled Release Society,  258  (196-207).  [PMID:28445743]
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9. Joshua Owen,Eloise Thomas,Jyothi Menon,Michael Gray,Irini Skaripa-Koukelli,Martin R Gill,Sheena Wallington,Rebecca L Miller,Katherine A Vallis,Robert Carlisle.  (2020-01-01)  Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation..  Journal of controlled release : official journal of the Controlled Release Society,  319  (222-233).  [PMID:31891732]
10. Paweł K Halik,Piotr F J Lipiński,Joanna Matalińska,Przemysław Koźmiński,Aleksandra Misicka,Ewa Gniazdowska.  (2020-08-23)  Radiochemical Synthesis and Evaluation of Novel Radioconjugates of Neurokinin 1 Receptor Antagonist Aprepitant Dedicated for NK1R-Positive Tumors..  Molecules (Basel, Switzerland),  25  ((16)): [PMID:32824729]
11. Poorya Najjari Nabi,Nasim Vahidfar,Mohammad Reza Tohidkia,Ali Asghar Hamidi,Yadollah Omidi,Ayuob Aghanejad.  (2021-02-01)  Mucin-1 conjugated polyamidoamine-based nanoparticles for image-guided delivery of gefitinib to breast cancer..  International journal of biological macromolecules,  174  (185-197).  [PMID:33516855]
12. N Willmott,T Murray,R Carlton,Y Chen,H Logan,G McCurrach,R G Bessent,J A Goldberg,J Anderson,J H McKillop.  (1991-01-01)  Development of radiolabelled albumin microspheres: a comparison of gamma-emitting radioisotopes of iodine (131I) and indium (111In/113mIn)..  International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology,  18  ((7)): (687-694).  [PMID:1787077]
13. B M Kinsey,R M Macklis,J M Ferrara,W W Layne,S J Burakoff,A I Kassis.  (1988-01-01)  Efficient conjugation of DTPA to an IgM monoclonal antibody in ascites fluid..  International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology,  15  ((3)): (285-292).  [PMID:2898458]
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15. T S Wang,S C Srivastava,R A Fawwaz,P Giacomini,S Ferrone,P Richards,M Hardy,P O Alderson.  (1984-08-01)  A comparison of the cyclic anhydride and mixed anhydride methods for 111In-DTPA chelation to monoclonal antibodies..  Nuklearmedizin. Nuclear medicine,  23  ((4)): (193-195).  [PMID:6483630]
16. M Fani,S Vranjes,S C Archimandritis,S Potamianos,S Xanthopoulos,P Bouziotis,A D Varvarigou.  (2002-11-16)  Labeling of monoclonal antibodies with 153Sm for potential use in radioimmunotherapy..  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine,  57  ((5)): (665-674).  [PMID:12433040]
17. MyeongJu Moon,Reju George Thomas,Seon-U Heo,Myong-Suk Park,Woo Kyun Bae,Suk Hee Heo,Nam Yeol Yim,Yong Yeon Jeong.  (2015-01-22)  A Hyaluronic Acid-Conjugated Gadolinium Hepatocyte-Specific T1 Contrast Agent for Liver Magnetic Resonance Imaging..  Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging,  17  ((4)): (497-503).  [PMID:25604386]
18. Yongbo Yang,Li Lin,Lijia Jing,Xiuli Yue,Zhifei Dai.  (2017-06-29)  CuInS.  ACS applied materials & interfaces,  9  ((28)): (23450-23457).  [PMID:28656760]
19. Farid N Faruqu,Julie Tzu-Wen Wang,Lizhou Xu,Luke McNickle,Eden Ming-Yiu Chong,Adam Walters,Mark Gurney,Aled Clayton,Lesley A Smyth,Robert Hider,Jane Sosabowski,Khuloud T Al-Jamal.  (2019-05-01)  Membrane Radiolabelling of Exosomes for Comparative Biodistribution Analysis in Immunocompetent and Immunodeficient Mice - A Novel and Universal Approach..  Theranostics,  9  ((6)): (1666-1682).  [PMID:31037130]
20. Yitan Wang, Li Chen, Yongsheng Yan, Ji Chen, Jiangdong Dai, Xiaohui Dai.  (2020)  Separation of adjacent heavy rare earth Lutetium (III) and Ytterbium (III) by task-specific ionic liquid Cyphos IL 104 embedded polymer inclusion membrane.  JOURNAL OF MEMBRANE SCIENCE,  610  (118263).  [10.1016/j.memsci.2020.118263]
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23. Yeneng Dai, Jinzhong Su, Kun Wu, Wenkang Ma, Bing Wang, Meixing Li, Pengfei Sun, Qingming Shen, Qi Wang, Quli Fan.  (2019)  Multifunctional Thermosensitive Liposomes Based on Natural Phase-Change Material: Near-Infrared Light-Triggered Drug Release and Multimodal Imaging-Guided Cancer Combination Therapy.  ACS Applied Materials & Interfaces,  11  (11): (10540–10553).  [PMID:30807086] [10.1021/acsami.8b22748]
24. Duan Xiaoyan, Li Jianbo, Lu Xiaoling.  (2019)  Radiolabeling of DNA nanostructure with 99mTc using DTPA as a chelate.  JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,  319  (1): (69-73).  [10.1007/s10967-018-6256-8]
25. Feng Fan, Yue Yu, Fei Zhong, Meng Gao, Tianmeng Sun, Jiaxin Liu, Huimao Zhang, Haisheng Qian, Wei Tao, Xianzhu Yang.  (2017)  Design of Tumor Acidity-Responsive Sheddable Nanoparticles for Fluorescence/Magnetic Resonance Imaging-Guided Photodynamic Therapy.  Theranostics,  7  (5): ( 1290–1302).  [PMID:28435466] [10.7150/thno.18557]
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28. Wanchao Yu, Xiaoshan Zheng, Mengxi Tan, Jingyi Wang, Binbin Wu, Junye Ma, Yishuai Pan, Baoliang Chen, Chiheng Chu.  (2024)  Field Quantification of Hydroxyl Radicals by Flow-Injection Chemiluminescence Analysis with a Portable Device.  ENVIRONMENTAL SCIENCE & TECHNOLOGY,  58  (6): (2808-2816).  [PMID:38227742] [10.1021/acs.est.3c09140]

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