| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| C475301-1g |
1g |
期货  |
| |
| C475301-5g |
5g |
期货 |
|
| 别名 | 3-[3-(胆酰胺丙基)二甲氨基]丙磺酸 水合物 | 3-[3-(胆酰胺丙基)二甲氨基]丙磺酸 水合物 |
|---|---|
| 英文别名 | 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate | CHAPS |
| 规格或纯度 | UltraBio™, 超纯级, ≥98% |
| 英文名称 | CHAPS hydrate |
| 产品介绍 |
CHAPS是一种非变性两性离子磺基甜菜碱洗涤剂，性温，可溶解膜蛋白和受体。它有助于打破蛋白质间的相互作用，是天然胆汁盐的衍生物。它具有小胶束分子量（6,150）和高临界胶束浓度（6 - 10 mM），允许通过透析将其从样本中除去。 应用 10mM CHAPS洗涤剂已用于离子交换色谱过程，旨在改善纯化。0.5w/v CHPS是蛋白质纯化中高盐缓冲液的一种成分，与HEPES、NaCl和EDTA一起使用。HEPES缓冲液已被用作免疫沉淀反应中的裂解缓冲液，补充了1% CHAP。 CHAPS is a non-denaturing, zwitterionic sulfobetaine detergent. It is mild and solubilizes membrane proteins and receptors. It is useful for breaking protein-protein interactions. It is a derivative of the naturally occurring bile salts. It has small micellar molecular weight (6,150) and high critical micellar concentration (6 - 10 mM) allowing it to be removed from samples by dialysis.10mM CHAPS detergent has been used in the process of ion-exchange chromatography for improved purification.0.5 w/v of CHAPS is a component of high salt buffer in protein purification alongside HEPES, NaCl and EDTA.HEPES buffer has been used as lysis buffer in immunoprecipitation, supplemented with 1% CHAPS. |
| 纯度 | ≥98% |
| IIUPAC Name | 3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate;hydrate |
|---|---|
| INCHI | 1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36;/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41);1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-;/m1./s1 |
| InChi Key | SJCUTFKCLFLIFE-JWTJKVBLSA-N |
| Smiles | CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C.O |
| Isomeric SMILES | C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C.O |
| 关联CAS | 75621-03-3 |
| 分子量 | 614.88 (anhydrous basis) |
| 溶解性 | H2O：0.1M，透明，无色 |
|---|
| 象形图 | GHS07 |
|---|---|
| 信号词 | 危险 |
| 危险声明 |
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P302+P352: 如皮肤沾染：用水充分清洗。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P405: 密闭存放 P403+P233: 存放在通风良好的地方。保持容器密闭。 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。 |
| WGK Germany | 1 |
| RIDADR | NONHforallmodesoftransport |
| 1. Wouter Meuleman,Judith Y M N Engwegen,Marie-Christine W Gast,Lodewyk F A Wessels,Marcel J T Reinders. (2009-02-28) Analysis of mass spectrometry data using sub-spectra.. BMC bioinformatics, 10 Suppl 1 (S51-S51). [PMID:19208154] |
| 2. Eric M Wexler,Andres Paucer,Harley I Kornblum,Theodore D Palmer,Theodore D Plamer,Daniel H Geschwind. (2009-05-07) Endogenous Wnt signaling maintains neural progenitor cell potency.. Stem cells (Dayton, Ohio), 27 ((5)): (1130-1141). [PMID:19418460] |
| 3. Marie Billaud,Roger Marthan,Jean-Pierre Savineau,Christelle Guibert. (2009-08-04) Vascular smooth muscle modulates endothelial control of vasoreactivity via reactive oxygen species production through myoendothelial communications.. PloS one, 4 ((7)): (e6432-e6432). [PMID:19649279] |
| 4. Eija Rintala,Mervi Toivari,Juha-Pekka Pitkänen,Marilyn G Wiebe,Laura Ruohonen,Merja Penttilä. (2009-10-07) Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae.. BMC genomics, 10 (461-461). [PMID:19804647] |
| 5. Marylin Torrentino-Madamet,Lionel Alméras,Jérôme Desplans,Yannick Le Priol,Maya Belghazi,Matthieu Pophillat,Patrick Fourquet,Yves Jammes,Daniel Parzy. (2011-01-13) Global response of Plasmodium falciparum to hyperoxia: a combined transcriptomic and proteomic approach.. Malaria journal, 10 (4-4). [PMID:21223545] |
| 6. Kathrin Schanda,Martin Hermann,Nadia Stefanova,Viktoria Gredler,Christine Bandtlow,Markus Reindl. (2011-01-18) Nogo-B is associated with cytoskeletal structures in human monocyte-derived macrophages.. BMC research notes, 4 (6-6). [PMID:21235733] |
| 7. Katherine M Horvath,Margaret Herbst,Haibo Zhou,Hongtao Zhang,Terry L Noah,Ilona Jaspers. (2011-08-06) Nasal lavage natural killer cell function is suppressed in smokers after live attenuated influenza virus.. Respiratory research, 12 (102-102). [PMID:21816072] |
| 8. Ana Paula Catunda Lemos,Judit Cervenak,Balázs Bender,Orsolya Ivett Hoffmann,Mária Baranyi,Andrea Kerekes,Anita Farkas,Zsuzsanna Bosze,László Hiripi,Imre Kacskovics. (2012-01-17) Characterization of the rabbit neonatal Fc receptor (FcRn) and analyzing the immunophenotype of the transgenic rabbits that overexpresses FcRn.. PloS one, 7 ((1)): (e28869-e28869). [PMID:22247762] |
| 9. Yahya Homsi,Thorsten Lang. (2017-02-09) The specificity of homomeric clustering of CD81 is mediated by its δ-loop.. FEBS open bio, 7 ((2)): (274-283). [PMID:28174692] |
| 10. Rongli Zhang,Yuyan Shen,Lin Zhou,Panjamaporn Sangwung,Hisashi Fujioka,Lilei Zhang,Xudong Liao. (2017-09-09) Short-term administration of Nicotinamide Mononucleotide preserves cardiac mitochondrial homeostasis and prevents heart failure.. Journal of molecular and cellular cardiology, 112 (64-73). [PMID:28882480] |
| 11. Kate E Yu,Do-Hyoung Kim,Yong-In Kim,Walton D Jones,J Eugene Lee. (2018-02-13) Mass Spectrometry-Based Screening Platform Reveals Orco Interactome in Drosophila melanogaster.. Molecules and cells, 41 ((2)): (150-159). [PMID:29429152] |
| 12. Kuang Shen,Kacper B Rogala,Hui-Ting Chou,Rick K Huang,Zhiheng Yu,David M Sabatini. (2019-11-11) Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex.. Cell, 179 ((6)): (1319-1329). [PMID:31704029] |
| 13. Jacqueline M Leung,Eiji Nagayasu,Yu-Chen Hwang,Jun Liu,Phillip G Pierce,Isabelle Q Phan,Robin A Prentice,John M Murray,Ke Hu. (2020-03-01) A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers.. BMC molecular and cell biology, 21 ((1)): (8-8). [PMID:32111164] |
| 14. S R Hough,J E Parks. (1997-12-31) Partial purification and localization of platelet-activating factor acetylhydrolase from bovine seminal plasma.. Journal of andrology, 18 ((5)): (540-548). [PMID:9349753] |
| 15. Koos Rooijers,Carolin Kolmeder,Catherine Juste,Joël Doré,Mark de Been,Sjef Boeren,Pilar Galan,Christian Beauvallet,Willem M de Vos,Peter J Schaap. (2011-01-07) An iterative workflow for mining the human intestinal metaproteome.. BMC genomics, 12 (6-6). [PMID:21208423] |
| 16. Li Guanglei, Chen Yao, Liu Fei, Bi Wenhua, Wang Chenxin, Lu Danfeng, Wen Dan. (2023) Portable visual and electrochemical detection of hydrogen peroxide release from living cells based on dual-functional Pt-Ni hydrogels. Microsystems & Nanoengineering, 9 (1): (1-10). [PMID:38033990] [10.1038/s41378-023-00623-y] |
| 17. Jie Zhao, Shuaiqian Wang, Diandian Jiang, Yan Lu, Yu Chen, Yong Tang, Jie Tang, Zhenju Jiang, Hongbin Lin, Wei Dong. (2023) Unravelling the interaction between α-SOH and myofibrillar protein based on spectroscopy and molecular dynamics simulation. Food Chemistry-X, 20 (100986). [PMID:38144868] [10.1016/j.fochx.2023.100986] |
| 18. Zhe Chen, Yunxia Wang. (2023) A label- and enzyme-free fluorescence assay based on thioflavin T–induced G-quadruplexes for the detection of telomerase activity. JOURNAL OF CHEMICAL RESEARCH, [10.1177/17475198221139085] |
| 19. Pengfei Dong, Longyi Zhu, Jing Huang, Jujie Ren, Jianping Lei. (2019) Electrocatalysis of cerium metal-organic frameworks for ratiometric electrochemical detection of telomerase activity. BIOSENSORS & BIOELECTRONICS, 138 (111313). [PMID:31108380] [10.1016/j.bios.2019.05.018] |
| 20. Min Zhang, Chong-sheng Peng, Xiao-bo Li. (2017) Human intestine and liver microsomal metabolic differences between C19-diester and monoester diterpenoid alkaloids from the roots of Aconitum carmichaelii Debx.. TOXICOLOGY IN VITRO, 45 (318). [PMID:28919359] [10.1016/j.tiv.2017.09.011] |
| 21. Feifei Gong, Huaxin Yang, Wen Sun, Junzi Cao, Wanhui Liu. (2016) Development and validation of a micellar electrokinetic capillary chromatography method for the determination of goserelin and related substances. ELECTROPHORESIS, 37 (4): (623-629). [PMID:26635325] [10.1002/elps.201500328] |
| 22. Yang Li,Ying Peng,Mengyue Wang,Pengfei Tu,Xiaobo Li. (2017-08-05) Human Gastrointestinal Metabolism of the Cistanches Herba Water Extract in Vitro: Elucidation of the Metabolic Profile Based on Comprehensive Metabolite Identification in Gastric Juice, Intestinal Juice, Human Intestinal Bacteria, and Intestinal Microsomes.. Journal of agricultural and food chemistry, 65 ((34)): (7447-7456). [PMID:28771352] |
首页
400-620-6333
7篇引用文献 
