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CHAPS 水合物

    级别和纯度:
  • ≥98%(HPLC)
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
C464942-1g
1g 现货 Stock Image
C464942-5g
5g 现货 Stock Image
C464942-25g
25g 现货 Stock Image
C464942-100g
100g 现货 Stock Image

基本描述

别名 3-[3-(胆酰胺丙基)二甲氨基]丙磺酸 水合物
英文别名 SCHEMBL1096579 | CHAPS (hydrate) | 3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1
规格或纯度 ≥98%(HPLC)
英文名称 CHAPS hydrate
产品介绍

CHAPS是一种非变性的两性离子磺基甜菜碱去污剂。它较为温和且能溶解膜蛋白和受体。它可用于破坏蛋白-蛋白之间的相互作用。它是天然存在的胆汁盐的衍生物。它具有较小的胶束分子量(6,150)以及较高临界胶束浓度(6 - 10mM),使其可通过透析而从样品中被去除。溶于水制成50 mg/ml溶液,可形成无色透明溶液。CHAPS水溶液可高压蒸汽灭菌。


应用

0.2 w/v的CHAPS已用于通过脑灌注去除脑内皮。2%(w/v) CHAPS已与硫脲和尿素一起在蛋白质提取中用作再水化缓冲液。10 mM CHAPS已与0.15 M NaCl, Tris–Cl, pH 7.6, EDTA一起在Western Blot分析中用作裂解缓冲液。CHAPS已在未成熟哺乳动物CNS的原位杂交方法中用作杂交缓冲液。

CHAPS is a non-denaturing, zwitterionic sulfobetaine detergent. It is mild and solubilizes membrane proteins and receptors. It is useful for breaking protein-protein interactions. It is a derivative of the naturally occurring bile salts. It has small micellar molecular weight (6,150) and high critical micellar concentration (6 - 10 mM) allowing it to be removed from samples by dialysis.A solution at 50 mg/ml in water yields a clear-colorless solution. Aqueous solutions of CHAPS can be autoclaved.0.2 w/v of CHAPS has been used to remove cerebral endothelium by brain perfusion. 2% (w/v) CHAPS has been used as rehydration buffer along with Thiourea and Urea in protein extraction. 10 mM CHAPS has been used along with 0.15 M NaCl, Tris–Cl, pH 7.6, EDTA as lysis buffer in Western Blot analysis. CHAPS has been used as hybridization buffer in in-situ hybridization method of immature mammalian CNS.

纯度 ≥98%(HPLC)

名称和识别符

PubChem SID 504770519
分子类型 小分子
IIUPAC Name 3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate;hydrate
INCHI 1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36;/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41);1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-;/m1./s1
InChi Key SJCUTFKCLFLIFE-JWTJKVBLSA-N
Smiles CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C.O
Isomeric SMILES C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C.O
关联CAS 75621-03-3
分子量 614.88 (anhydrous basis)

安全和危险性(GHS)

象形图 GHS07
信号词 危险
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激

预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P264: 处理后要彻底洗手。

P271: 仅在室外或通风良好的地方使用。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P321: 特殊处理(请参阅此标签上的...)。

P302+P352: 如皮肤沾染:用水充分清洗。

P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。

P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。

P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。

P405: 密闭存放

P403+P233: 存放在通风良好的地方。保持容器密闭。

P501: 将内容物/容器处理到。。。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续:寻求医疗帮助。

P332+P317: 如果出现皮肤刺激:请寻求医疗帮助。

P319: 如果你感到不适,请寻求医疗帮助。

WGK Germany 1
RIDADR NONHforallmodesoftransport

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批号(Lot Number) 证书类型 货号
D2503266 分析证书 C464942
D2503267 分析证书 C464942
D2503268 分析证书 C464942
D2503269 分析证书 C464942
G2326025 分析证书 C464942

此产品的引用文献

引用文献

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