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| 英文名称 | COX-2-IN-30 |
|---|---|
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 抑制剂 |
| 产品介绍 |
COX-2-IN-30 is a benzenesulfonamide derivative, as well as an orally active and dual inhibitor of COX ( IC 50 =49 nM for COX-2 , 10.4 μM for COX-1 ) and 5-LOX ( IC 50 =2.4 μM). COX-2-IN-30 also inhibits transmembrane hCA IX and hCA XII isoform with nanomolar calss K i values. COX-2-IN-30 exhibits analgesic, anti-inflammatory, and ulcerogenic activities, and does not show acute gastric effect. |
| 分子量 | 384.41 |
|---|