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Coelenterazine

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
C1375499-1mg
1mg 期货 Stock Image
C1375499-5mg
5mg 期货 Stock Image

基本描述

英文别名 2-(p-Hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzyl-imidazo[1 | 2-a]pyrazin-3-(7H)-one
规格或纯度 分子生物学级, ≥95%(TLC)
英文名称 Coelenterazine
储存温度 避光,-20°C储存,充氩
运输条件 超低温冰袋运输
产品介绍


Coelenterazine is a luminophore found in aquatic organisms and is the substrate for many luciferase enzymes, including Renilla reniformis, Gaussia and aequorins. It is commonly used for bioluminescent calcium detection and the monitoring of reporter genes in BRET (Bioluminescence Resonance Energy Transfer), ELISA and HTS methods as well as chemiluminescent detection of superoxide anions and peroxynitrite in cells or tissues.
Note: It is not recommended to store dissolved coelenterazine at -20°C or -70°C. Coelenterazine is a high energy dioxetanone ring structure that will spontaneously decompose even at low temperatures.

纯度 ≥95%(TLC)

名称和识别符

IIUPAC Name 8-benzyl-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]imidazo[1,2-a]pyrazin-3-ol
INCHI 1S/C26H21N3O3/c30-20-10-6-18(7-11-20)15-23-26(32)29-16-24(19-8-12-21(31)13-9-19)27-22(25(29)28-23)14-17-4-2-1-3-5-17/h1-13,16,30-32H,14-15H2
InChi Key LNCOEGVEEQDKGX-UHFFFAOYSA-N
Smiles C1=CC=C(C=C1)CC2=NC(=CN3C2=NC(=C3O)CC4=CC=C(C=C4)O)C5=CC=C(C=C5)O
Isomeric SMILES C1=CC=C(C=C1)CC2=NC(=CN3C2=NC(=C3O)CC4=CC=C(C=C4)O)C5=CC=C(C=C5)O
分子量 423.46
Reaxy-Rn 37031400
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=37031400&ln=

化学和物理性质

溶解性 Soluble in methanol or ethanol (NOT in DMSO).
分子量 423.500 g/mol
XLogP3 5.500
氢键供体数Hydrogen Bond Donor Count 3
氢键受体数Hydrogen Bond Acceptor Count 5
可旋转键计数Rotatable Bond Count 5
精确质量Exact Mass 423.158 Da
单同位素质量Monoisotopic Mass 423.158 Da
拓扑极表面积Topological Polar Surface Area 90.900 Ų
重原子数Heavy Atom Count 32
形式电荷Formal Charge 0
复杂度Complexity 585.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性(GHS)

危险声明

H413: 可能对水生生物造成长期的有害影响

预防措施声明

P273: 避免释放到环境中。

P501: 将内容物/容器处理到。。。

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

溶液计算器