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硫酸软骨素钠盐（鲨鱼）

44篇引用文献 COA COA
    级别和纯度:
  • ≥95%
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
C107703-250mg
 250mg 现货 Stock Image
C107703-1g
 1g 现货 Stock Image
C107703-5g
 5g 现货 Stock Image
C107703-25g
 25g 现货 Stock Image
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查看相关系列
Amino Acid/Protein Metabolism (4559) Immunology/Inflammation (1938) Metabolic Enzyme/Protease (4889) MMP (148) NO Synthase (134) 碳水化合物 (82)
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基本描述

别名 鲨鱼软骨素
英文别名 Sodium chondroitin sulfate
规格或纯度 ≥95%
英文名称 Chondroitin sulfate sodium salt from shark cartilage
生化机理 软骨素是一种氨基葡萄糖（GAG），是由β-葡萄糖醛酸-(1→3)N-乙酰基-β-半乳糖胺[β-GlcA-(1→3)-GalNAc-(1→4)]组成的天然聚合物。硫酸化可能发生在半乳糖胺分子的 6 位和/或 4 位，任何单个二糖单元都有可能被 6-硫酸化、4-硫酸化、4,6-二硫酸化或未硫酸化。
储存温度 2-8°C储存
运输条件 冰袋运输
产品介绍

软骨素是一种氨基葡聚糖 (GAG)，是 N-乙酰半乳糖胺 (GalNAc) 和葡萄糖醛酸 (GlcA) 交替单位的多糖链，可在 GalNAc 和 GlcA 单位上发生硫酸化。软骨素及其硫酸盐经常附着在蛋白质上形成蛋白聚糖。

应用：

硫酸软骨素广泛用于生物工程等研究领域。硫酸软骨素可作为生物材料共聚物或表面衍生试剂用于药物传递载体、组织工程装置和生物支架的开发。硫酸软骨素可用于开发生物相容性结构，如水凝胶、海绵、生物膜、微球和胶束。
软骨素在软骨细胞、中性细胞和一些肿瘤细胞中起到调节作用。硫酸软骨素B被用来研究ß肽链(1-42) 细胞毒性。

Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans.
Chondroitin sulfate is used in a wide variety of areas of research such as bioengineering. Chondroitin sulfate may be used as a biomaterial copolymer or surface derivatization reagent in the development of drug delivery vehicles, tissue engineering devices and bioscaffolds. Chondroitin sulfate may be used for the development of biocompatible structures such as hydrogels, sponges, biofilms, microspheres and micelles.
纯度 ≥95%

名称和识别符

PubChem SID 504753258
EC号 232-696-9
IIUPAC Name (2S,3S,4S,5R,6R)-6-[(2R,3R,4R,5R,6R)-3-acetamido-2,5-dihydroxy-6-sulfooxyoxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
INCHI 1S/C13H21NO15S/c1-2(15)14-3-8(7(19)13(28-11(3)22)29-30(23,24)25)26-12-6(18)4(16)5(17)9(27-12)10(20)21/h3-9,11-13,16-19,22H,1H3,(H,14,15)(H,20,21)(H,23,24,25)/t3-,4+,5+,6-,7-,8-,9+,11-,12-,13-/m1/s1
InChi Key KXKPYJOVDUMHGS-OSRGNVMNSA-N
Smiles CC(=O)NC1C(C(C(OC1O)OS(=O)(=O)O)O)OC2C(C(C(C(O2)C(=O)O)O)O)O
Isomeric SMILES CC(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1O)OS(=O)(=O)O)O)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C(=O)O)O)O)O
Reaxy-Rn 29675846
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29675846&ln=

化学和物理性质

密度 1.159
敏感性 对光敏感
分子量 463.370 g/mol
XLogP3 -4.800
氢键供体数Hydrogen Bond Donor Count 8
氢键受体数Hydrogen Bond Acceptor Count 15
可旋转键计数Rotatable Bond Count 6
精确质量Exact Mass 463.063 Da
单同位素质量Monoisotopic Mass 463.063 Da
拓扑极表面积Topological Polar Surface Area 267.000 Ų
重原子数Heavy Atom Count 30
形式电荷Formal Charge 0
复杂度Complexity 739.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 10
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS07,   GHS08
信号词 Danger
WGK Germany 3
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

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批号(Lot Number) 证书类型 货号
C1809094 分析证书 C107703
A2207919 分析证书 C107703
A22071110 分析证书 C107703
I2510105 分析证书 C107703
G2404190 分析证书 C107703
G2404191 分析证书 C107703
G2404192 分析证书 C107703
G2404193 分析证书 C107703
G2404536 分析证书 C107703
E1529015 分析证书 C107703
F2228165 分析证书 C107703
F2228227 分析证书 C107703
F2228228 分析证书 C107703
C1809095 分析证书 C107703
G2225022 分析证书 C107703

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可替换产品

  1. 软骨素二糖 δdi-0S 钠盐
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  2. 硫酸软骨素A钠盐
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  3. 来自牛软骨的硫酸软骨素钠盐
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  4. 软骨素二糖δ二-6S钠盐
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  5. 硫酸软骨素(鲨鱼)
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    • 10mM in Water

    ¥205.90

  6. 硫酸软骨素A钠盐
    硫酸软骨素A钠盐
    • mixture of isomers, main component: chondroitin 4-sulfate

    ¥92.90

  7. 软骨素二糖 Δdi-4S 钠盐
    软骨素二糖 Δdi-4S 钠盐
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  8. 软骨素硫酸钠盐
    软骨素硫酸钠盐
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    ¥59.90

  9. 硫酸软骨素C钠盐
    硫酸软骨素C钠盐
    • ≥90%
    • mixture of isomers,From sharks

    ¥88.90

  10. 硫酸软骨素B钠盐
    硫酸软骨素B钠盐
    • ≥90%
    • lyophilized powder,from porcine intestinal mucosa,lyophilized powder;average MW 30-40KDa

    ¥799.90

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引用文献

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