基本描述

别名	(R)-α-甘油氯 \| (R)-3-氯甘油
英文别名	Q27109076 \| (R)-.ALPHA.-CHLOROHYDRIN \| HMS2232L24 \| (R)-(-)-3-Chloro-1,2-propanediol, 97%, optical purity ee: 98% (GLC) \| 4-fluroaniline \| (2R)-(-)-3-Chloropropane-1,2-diol \| (R)-3-Chloro-1,2-propanediol \| 64YMO02KAE \| 1,2-Propanediol, 3-chloro-, (R)- \| A
规格或纯度	≥97%
英文名称	(R)-(-)-3-Chloro-1,2-propanediol
应用	化工、有机化工原料、有机中间体、医药中间体。
运输条件	常规运输
产品介绍	化工、有机化工原料、有机中间体、医药中间体。
纯度	≥97%

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	504757325
分子类型	小分子
IIUPAC Name	(2R)-3-chloropropane-1,2-diol
INCHI	1S/C3H7ClO2/c4-1-3(6)2-5/h3,5-6H,1-2H2/t3-/m0/s1
InChi Key	SSZWWUDQMAHNAQ-VKHMYHEASA-N
Smiles	C(C(CCl)O)O
Isomeric SMILES	C([C@H](CCl)O)O
UN Number	2689
分子量	110.54
Beilstein号	2202928
Reaxy-Rn	635684
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=635684&ln=

化学和物理性质

密度	1.32
敏感性	易吸湿
折光率	1.479-1.481
比旋光度	-9 ° (C=2, H2O)
闪点(℉)	275 °F
闪点(℃)	135 °C
沸点	95°C
熔点	213°C
分子量	110.540 g/mol
XLogP3	-0.500
氢键供体数Hydrogen Bond Donor Count	2
氢键受体数Hydrogen Bond Acceptor Count	2
可旋转键计数Rotatable Bond Count	2
精确质量Exact Mass	110.013 Da
单同位素质量Monoisotopic Mass	110.013 Da
拓扑极表面积Topological Polar Surface Area	40.500 Å²
重原子数Heavy Atom Count	6
形式电荷Formal Charge	0
复杂度Complexity	32.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	1
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS05, GHS06, GHS07, GHS08
信号词	危险
危险声明	H290: 可能腐蚀金属 H300: 吞咽致命 H301: 吞咽会中毒 H311: 皮肤接触有毒 H315: 引起皮肤刺激 H318: 造成严重的眼睛损伤 H330: 吸入致命 H331: 吸入会中毒 H351: 怀疑引起遗传缺陷 H360: 可能损害生育力或未出生的孩子 H370: 对器官造成损害 H372: 通过长时间或反复暴露对器官造成损害
预防措施声明	P234: 仅保存在原始容器中 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P271: 仅在室外或通风良好的地方使用。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P284: 如果通风不良，请佩戴呼吸防护装置。 P320: 迫切需要特殊治疗（请参阅此标签上的...）。 P321: 特殊处理（请参阅此标签上的...）。 P330: 漱口 P390: 吸收溢出物以防止材料损坏。 P302+P352: 如皮肤沾染：用水充分清洗。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P361+P364: 立即脱掉所有沾染的衣服，清洗后方可重新使用。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P405: 密闭存放 P406: 存放在带有耐腐蚀内衬的耐腐蚀/ ...容器中。 P403+P233: 存放在通风良好的地方。保持容器密闭。 P501: 将内容物/容器处理到。。。 P203: 使用前，获取、阅读并遵守所有安全说明。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P316: 如果吞咽：立即寻求紧急医疗救助。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。 P318: 如果暴露或担心，请就医。 P317: 寻求紧急医疗救助。 P308+P316: 如果暴露或担心：立即寻求紧急医疗救助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P316: 立即寻求紧急医疗救助。 P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany	3
个人防护装备	Eyeshields,Faceshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

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通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到13个结果

批号(Lot Number)	证书类型	货号
K2125583	分析证书	C106058
K2125585	分析证书	C106058
G2028152	分析证书	C106058
G2419147	分析证书	C106058
G2419146	分析证书	C106058
D1606014	分析证书	C106058
K2201287	分析证书	C106058
K2201313	分析证书	C106058
K2201319	分析证书	C106058
F2305999	分析证书	C106058
F23051001	分析证书	C106058
F23051046	分析证书	C106058
B2525013	分析证书	C106058

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引用文献

1. Hao Zhang,Guoqing Qian,Xiao Ling,Jianwei Zhao,et al. (2008-07-01) [Effects of S-alpha-chlorohydrin on male ICR mice fertility].. Wei sheng yan jiu = Journal of hygiene research, 37 ((2)): (133-136). [PMID:18589591]
2. D Lupaşcu,Cristina Tuchiluş,Lenuţa Profire. (2008-08-06) [Research concerning rutin semisynthetic derivatives. Synthesis, physico-chemical and microbiological characterisation of some new rutin-isoniazid derivatives].. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 112 ((1)): (249-252). [PMID:18677936]
3. J C Lee,I S Shin,T H Ahn,K H Kim,C Moon,S H Kim,D H Shin,S C Park,Y B Kim,J C Kim. (2008-12-03) Developmental toxic potential of 1,3-dichloro-2-propanol in Sprague-Dawley rats.. Regulatory toxicology and pharmacology : RTP, 53 ((1)): (63-69). [PMID:19047007]
4. Lu-xin Zhang,Jin-ping Yang,Dai-li Liu. (2009-04-11) [Gas chromatography for determination of 1, 3-dichloro-2-propanol in air of working places].. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 26 ((8)): (492-493). [PMID:19358767]
5. Antonia María Carro,Paula González,Noelia Fajar,Rosa Antonia Lorenzo,Rafael Cela. (2009-04-11) Solid-phase micro-extraction procedure for the determination of 1,3-dichloro-2-propanol in water by on-fibre derivatisation with bis(trimethylsilyl)trifluoroacetamide.. Analytical and bioanalytical chemistry, 394 ((3)): (893-901). [PMID:19360402]
6. Ching-Yu Lin,Pei-hsuan Hung,Catherine A VandeVoort,Marion G Miller. (2009-06-06) 1H NMR to investigate metabolism and energy supply in rhesus macaque sperm.. Reproductive toxicology (Elmsford, N.Y.), 28 ((1)): (75-80). [PMID:19490998]
7. Helen Hurst,Richard H Clothier,Margaret Pratten. (2009-08-04) An evaluation of the chick cardiomyocyte micromass system for identification of teratogens in a blind trial.. Reproductive toxicology (Elmsford, N.Y.), 28 ((4)): (503-510). [PMID:19646523]
8. Sun Young Park,Young Hun Kim,Young Hee Kim,Sang-Joon Lee. (2009-09-05) 1,3-Dichloro-2-propanol induces apoptosis via both calcium and ROS in mouse melanoma cells.. Biotechnology letters, 32 ((1)): (45-51). [PMID:19731046]
9. Gary Williams,Jean-Charles Leblanc,R Woodrow Setzer. (2010-02-02) Application of the margin of exposure (MoE) approach to substances in food that are genotoxic and carcinogenic: example: (CAS No. 96-23-1) 1,3-dichloro-2-propanol (DCP).. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48 Suppl 1 (S57-S62). [PMID:20113855]
10. Shuwu Xie,Yan Zhu,Li Ma,Yingying Lu,Jieyun Zhou,Youlun Gui,Lin Cao. (2010-04-23) Genome-wide profiling of gene expression in the epididymis of alpha-chlorohydrin-induced infertile rats using an oligonucleotide microarray.. Reproductive biology and endocrinology : RB&E, 8 (37-37). [PMID:20409345]
11. Angus M Brown,John Skamarauskas,Timothy Lister,Ameneh Madjd,David E Ray. (2010-12-16) Differential susceptibility of astrocytic and neuronal function to 3-chloropropanediol in the rat inferior colliculus.. Journal of neurochemistry, 116 ((6)): (996-1004). [PMID:21155803]
12. Nadiya Bakhiya,Klaus Abraham,Rainer Gürtler,Klaus Erich Appel,Alfonso Lampen. (2011-02-26) Toxicological assessment of 3-chloropropane-1,2-diol and glycidol fatty acid esters in food.. Molecular nutrition & food research, 55 ((4)): (509-521). [PMID:21351250]
13. Zheng-Yi Tao,Xin-Sheng Chai,Shu-Bin Wu. (2011-08-05) Determination of epichlorohydrin and 1,3-dichloro-2-propanol in synthesis of cationic etherifying reagent by headspace gas chromatography.. Journal of chromatography. A, 1218 ((37)): (6518-6521). [PMID:21813132]
14. Paula González,Inés Racamonde,Antonia M Carro,Rosa A Lorenzo. (2011-08-06) Combined solid-phase extraction and gas chromatography-mass spectrometry used for determination of chloropropanols in water.. Journal of separation science, 34 ((19)): (2697-2704). [PMID:21818849]
15. I Racamonde,P González,R A Lorenzo,A M Carro. (2011-08-31) Determination of chloropropanols in foods by one-step extraction and derivatization using pressurized liquid extraction and gas chromatography-mass spectrometry.. Journal of chromatography. A, 1218 ((39)): (6878-6883). [PMID:21875707]
16. Shouji Takahashi,Yuki Obana,Shohei Okada,Katsumasa Abe,Yoshio Kera. (2011-10-01) Complete detoxification of tris(1,3-dichloro-2-propyl) phosphate by mixed two bacteria, Sphingobium sp. strain TCM1 and Arthrobacter sp. strain PY1.. Journal of bioscience and bioengineering, 113 ((1)): (79-83). [PMID:21956155]
17. Hassan M Badawi. (2011-12-14) A study of the molecular structure and vibrational spectra of 1,3-dichloro-2-propanol and 1,1,1-trichloro-2-methyl-2-propanol (chlorobutanol).. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 87 (11-14). [PMID:22154261]
18. Brian D Craft,Kornél Nagy,Laurence Sandoz,Frédéric Destaillats. (2011-12-16) Factors impacting the formation of monochloropropanediol (MCPD) fatty acid diesters during palm (Elaeis guineensis) oil production.. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 29 ((3)): (354-361). [PMID:22168150]
19. D Lupaşcu,Cristina Tuchiluş,Maria Sutu,Alexandra Neagu,Lenuţa Profire. (2012-01-27) [Synthesis and characterization of some new rutin and 7-aminocephalosporanic acid derivatives].. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 115 ((4)): (1278-1282). [PMID:22276483]
20. Hao Zhang,Huan Yu,Xia Wang,Weiwei Zheng,Bei Yang,Jingbo Pi,Gengsheng He,Weidong Qu. (2012-08-24) (S)-α-chlorohydrin inhibits protein tyrosine phosphorylation through blocking cyclic AMP - protein kinase A pathway in spermatozoa.. PloS one, 7 ((8)): (e43004-e43004). [PMID:22916194]
21. B D Craft,A Chiodini,J Garst,M Granvogl. (2012-10-02) Fatty acid esters of monochloropropanediol (MCPD) and glycidol in refined edible oils.. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 30 ((1)): (46-51). [PMID:23020600]
22. Jianxia Sun,Shun Bai,Weibin Bai,Feiyan Zou,Lei Zhang,Guoqiang Li,Yunfeng Hu,Mingwei Li,Rian Yan,Zhijian Su,Yadong Huang. (2014-02-13) 1,3-Dichloro-2-propanol inhibits progesterone production through the expression of steroidogenic enzymes and cAMP concentration in Leydig cells.. Food chemistry, 154 (330-336). [PMID:24518350]
23. Z Zelinková,O Novotný,J Schůrek,J Velísek,J Hajslová,M Dolezal. (2008-05-20) Occurrence of 3-MCPD fatty acid esters in human breast milk.. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 25 ((6)): (669-676). [PMID:18484295]
24. Nithar Ranjan Madhu,Bhanumati Sarkar,Surjyo Jyoti Biswas,Biplab Kumar Behera,Ashis Patra. (2011-10-05) Evaluating the anti-fertility potential of α-chlorohydrin on testis and spermatozoa in the adult male wild Indian house rat (Rattus rattus).. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 30 ((2)): (93-102). [PMID:21967454]
25. Colin L Willis. (2011-12-07) Imaging in vivo astrocyte/endothelial cell interactions at the blood-brain barrier.. Methods in molecular biology (Clifton, N.J.), 814 (515-529). [PMID:22144329]
26. K Yamazaki,M Ogiso,S Isagawa,T Urushiyama,T Ukena,N Kibune. (2012-08-23) A new, direct analytical method using LC-MS/MS for fatty acid esters of 3-chloro-1,2-propanediol (3-MCPD esters) in edible oils.. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 30 ((1)): (52-68). [PMID:22909228]

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复溶计算器

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货号 (SKU)	包装规格	是否现货
C106058-5g	5g	现货
C106058-25g	25g	现货
C106058-100g	100g	现货
C106058-500g	500g	现货

(R)-(-)-3-氯-1,2-丙二醇

库存信息

库存信息

库存信息

库存信息

基本描述

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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此产品的引用文献

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器