| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| B608256-5mg |
5mg |
期货  |
| |
| B608256-25mg |
25mg |
期货 |
|
| 别名 | 布卡星 |
|---|---|
| 英文别名 | BUTIKACIN [INN] | Butikacin (USAN/INN) | UK 18,892 | D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1-4))-N1-(4-amino-2-hydroxybutyl)-2-deoxy-, (S)- | UK18892 | UK-18892 | Butikacine | (-)-E-Caryop |
| 规格或纯度 | Moligand™ |
| 英文名称 | butikacin |
| 分子类型 | 小分子 |
|---|---|
| IIUPAC Name | (2R,3R,4S,5S,6R)-2-[(1R,2S,3S,4R,6S)-6-amino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[[(2S)-4-amino-2-hydroxybutyl]amino]-2-hydroxycyclohexyl]oxy-6-(aminomethyl)oxane-3,4,5-triol |
| INCHI | 1S/C22H45N5O12/c23-2-1-7(29)5-27-9-3-8(25)19(38-22-17(34)16(33)14(31)10(4-24)36-22)18(35)20(9)39-21-15(32)12(26)13(30)11(6-28)37-21/h7-22,27-35H,1-6,23-26H2/t7-,8-,9+,10+,11+,12-,13+,14+,15+,16-,17+,18-,19+,20-,21+,22+/m0/s1 |
| InChi Key | OCFOTEIMZBKQFS-DGMGPCKZSA-N |
| Smiles | NCC[C@@H](CN[C@@H]1C[C@H](N)[C@H]([C@@H]([C@H]1O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)N)O)O)O[C@H]1O[C@H](CN)[C@H]([C@@H]([C@H]1O)O)O)O |
| Isomeric SMILES | C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC[C@H](CCN)O)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)O)N |
| PubChem CID | 11954318 |
| 分子量 | 571.600 g/mol |
|---|---|
| XLogP3 | -7.600 |
| 氢键供体数Hydrogen Bond Donor Count | 13 |
| 氢键受体数Hydrogen Bond Acceptor Count | 17 |
| 可旋转键计数Rotatable Bond Count | 11 |
| 精确质量Exact Mass | 571.306 Da |
| 单同位素质量Monoisotopic Mass | 571.306 Da |
| 拓扑极表面积Topological Polar Surface Area | 315.000 Ų |
| 重原子数Heavy Atom Count | 39 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 748.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 16 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 1. Carter AJ. (1979) Cochlear toxicity of butikacin (UK-18,892), a new semisynthetic aminoglycoside antibiotic, in guinea pigs.. Antimicrob Agents Chemother, 16 (3): (362-5). [PMID:507791] |
| 2. Jevons S, Cheeseman HE, Brammer KW. (1978) In vitro studies with UK-18,892, a new aminoglycoside antibiotic.. Antimicrob Agents Chemother, 14 (3): (277-80). [PMID:708005] |
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