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基本描述
| 英文名称 | BMS-986251 |
|---|---|
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 抑制剂 |
| 产品介绍 |
BMS-986251 is an orally active and selective RORγt inverse agonist with an EC 50 of 12 nM for RORγt GAL4. BMS-986251 inhibits IL-17 with an EC 50 of 24 nM in human whole blood assay. BMS-986251 demonstrates robust efficacy in mouse acanthosis and Imiquimod -induced models (preclinical models of psoriasis). |
名称和识别符
| 分子量 | 667.61 |
|---|
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