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基本描述
| 英文名称 | A-800141 |
|---|---|
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 抑制剂 |
| 产品介绍 |
A-800141 is an orally active and selective MetAP2 inhibitor with an IC 50 of 12 nM. A-800141 has weak inhibitory activity for MetAP1 ( IC 50 : 36 μM). GAPDH can be used as a biomarker to monitor the MetAP2 inhibition of A-800141. A-800141 has antiangiogenic and anticancer activity in a variety of xenograft tumor models. |
名称和识别符
| 分子量 | 442.57 |
|---|
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