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基本描述
| 英文名称 | A-9758 |
|---|---|
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 抑制剂 |
| 产品介绍 |
A-9758 is a RORγ ligand and a potent, selective RORγt inverse agonist ( IC 50 =5 nM), and exhibits robust potency against IL-17A release. A-9758 is effective in suppressing both Th17 differentiation and Th17 effector function. A-9758 significantly attenuates IL-23 driven psoriasiform dermatitis and is effective in blocking skin and joint inflammation. |
名称和识别符
| 分子量 | 527.36 |
|---|
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