基本描述

别名	5-氨基-2,4-嘧啶二醇 \| 5-氨基-2,4-二羟基嘧啶
英文别名	InChI=1/C4H5N3O2/c5-2-1-6-4(9)7-3(2)8/h1H,5H2,(H2,6,7,8,9 \| 5-Amino-2,4-dihydroxypyrimidine \| EN300-95642 \| Z276550526 \| 5-Aminouracil, 98% \| DB03792 \| 2,4(1H,3H)-Pyrimidinedione, 5-amino- \| AKOS001603829 \| F16509 \| WBU \| UNII-R2O7EKY9G9 \| 5-amino uracil
规格或纯度	≥98%
英文名称	5-Aminouracil
应用	用作生化研究试剂
运输条件	常规运输
产品介绍	溶于稀酸，不溶于水。具两性。可形成金属盐和苦味酸盐用作生化研究试剂
纯度	≥98%

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	488181876
EC号	213-252-3
分子类型	小分子
IIUPAC Name	5-amino-1H-pyrimidine-2,4-dione
INCHI	1S/C4H5N3O2/c5-2-1-6-4(9)7-3(2)8/h1H,5H2,(H2,6,7,8,9)
InChi Key	BISHACNKZIBDFM-UHFFFAOYSA-N
Smiles	C1=C(C(=O)NC(=O)N1)N
Isomeric SMILES	C1=C(C(=O)NC(=O)N1)N
分子量	127.1
Beilstein号	127250
Reaxy-Rn	127250
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=127250&ln=

化学和物理性质

熔点	>300°C
分子量	127.100 g/mol
XLogP3	-1.500
氢键供体数Hydrogen Bond Donor Count	3
氢键受体数Hydrogen Bond Acceptor Count	3
可旋转键计数Rotatable Bond Count	0
精确质量Exact Mass	127.038 Da
单同位素质量Monoisotopic Mass	127.038 Da
拓扑极表面积Topological Polar Surface Area	84.200 Å²
重原子数Heavy Atom Count	9
形式电荷Formal Charge	0
复杂度Complexity	196.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS07
信号词	警告
危险声明	H302: 吞食有害
预防措施声明	P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P312: 如误吞咽：如感觉不适，呼叫急救中心/医生。 P501: 将内容物/容器处理到。。。
WGK Germany	3
RTECS	YQ8740000
个人防护装备	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

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找到9个结果

批号(Lot Number)	证书类型	货号
H2111081	分析证书	A119337
C2301577	分析证书	A119337
L2207079	分析证书	A119337
L2207087	分析证书	A119337
L2207088	分析证书	A119337
L2207089	分析证书	A119337
I1820251	分析证书	A119337
I1820250	分析证书	A119337
C2301576	分析证书	A119337

引用文献

1. J E Thomas,A M Zimmerman. (1983-05-01) The action of 5-amino uracil on log growth and division-synchronized Tetrahymena.. Cell and tissue kinetics, 16 ((3)): (285-301). [PMID:6188532]
2. M H Navarrete,A Cuadrado,J L Cánovas. (1983-10-15) Partial elimination of G1 and G2 periods in higher plant cells by increasing the S period.. Experimental cell research, 148 ((2)): (273-280). [PMID:6628558]
3. F Cortés,P Escalza,M D Sosa,J L López-Campos. (1983-10-15) Cytological demonstration of DNA synthesis inhibition at late S by 5-amino-uracil.. Experimental cell research, 148 ((2)): (503-507). [PMID:6628567]
4. D Davidson. (1982-12-01) Recovery from the 5-AU induced blockage in interphase: evidence for differential recovery.. Cytologia, 47 ((3-4)): (545-553). [PMID:7166054]
5. O A Fathalla. (2000-01-01) Synthesis of new pyrazolo[1,5-a]pyrimidine derivative using 5-aminouracil and ketene dithioacetal.. Archives of pharmacal research, 22 ((6)): (571-574). [PMID:10615862]
6. V S Rana,K N Ganesh. (2000-02-10) Recognition of 5-aminouracil (U(#)) in the central strand of a DNA triplex: orientation selective binding of different third strand bases.. Nucleic acids research, 28 ((5)): (1162-1169). [PMID:10666458]
7. R Sen,S Ghosh. (2000-06-30) Induction of premature mitosis in S-blocked onion cells.. Cell biology international, 22 ((11-12)): (867-874). [PMID:10873298]
8. Francisco Hueso-Ureña,Nuria A Illán-Cabeza,Miguel N Moreno-Carretero,José M Martínez-Martos,María J Ramírez-Expósito. (2003-04-02) Synthesis and spectroscopic studies on the new Schiff base derived from the 1:2 condensation of 2,6-diformyl-4-methylphenol with 5-aminouracil (BDF5AU) and its transition metal complexes. Influence on biologically active peptides-regulating aminopeptidases.. Journal of inorganic biochemistry, 94 ((4)): (326-334). [PMID:12667703]
9. Del Campo,R Samaniego,J F Giménez-Abián,G Giménez-Martín,J F López-Sáez,S Moreno Díaz de la Espina,C De la Torre. (2003-11-25) G2 checkpoint targets late replicating DNA.. Biology of the cell, 95 ((8)): (521-526). [PMID:14630389]
10. Akos Bányász,Thomas Gustavsson,Erno Keszei,Roberto Improta,Dimitra Markovitsi. (2008-07-04) Effect of amino substitution on the excited state dynamics of uracil.. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 7 ((7)): (765-768). [PMID:18597022]
11. Slawomir Boncel,Krzysztof Walczak. (2009-02-17) Novel acyclic amide-conjugated nucleosides and their analogues.. Nucleosides, nucleotides & nucleic acids, 28 ((2)): (103-117). [PMID:19219740]
12. Paulina Spisz,Witold Kozak,Lidia Chomicz-Mańka,Samanta Makurat,Karina Falkiewicz,Artur Sikorski,Anna Czaja,Janusz Rak,Magdalena Zdrowowicz. (2020-09-05) 5-(N-Trifluoromethylcarboxy)aminouracil as a Potential DNA Radiosensitizer and Its Radiochemical Conversion into N-Uracil-5-yloxamic Acid.. International journal of molecular sciences, 21 ((17)): [PMID:32883013]
13. D Suciu. (1991-01-01) Reproductive death of Chinese hamster V79 cells after exposure to chemical inhibitors of DNA synthesis.. The International journal of biochemistry, 23 ((11)): (1245-1249). [PMID:1724427]
14. F Cortés,S Mateos. (1991-03-01) Premature onset of mitosis and potentiation of chromosome damage induced by poly-D-lysine in plant cells: evidence for G2 repair.. Mutation research, 247 ((1)): (147-151). [PMID:2002799]
15. A González-Fernández,P Hernández,J F López-Sáez. (1985-04-01) Effect of caffeine and adenosine on G2 repair: mitotic delay and chromosome damage.. Mutation research, 149 ((2)): (275-281). [PMID:3982446]
16. S W Armstrong,D Davidson. (1982-03-01) Differences in protein content of sister nuclei: evidence from binucleate and mononucleate cells.. Canadian journal of biochemistry, 60 ((3)): (371-378). [PMID:7083048]
17. A González-Fernández,J F López-Sáez. (1982-12-01) Effect of caffeine on G2 repair and its reversion by adenosine.. Mutation research, 106 ((2)): (255-264). [PMID:7155167]
18. A Del Campo,M Bracho,L Marcano,J Guíñez,C De la Torre. (2005-09-29) DNA injury induced by 5-aminouracil and caffeine in G2 checkpoints path of higher plant cells.. Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al, 29 ((2)): (169-176). [PMID:16187495]
19. K K Upadhyay,Ajit Kumar. (2010-07-07) Al3+ selective an efficient colorimetric receptor derived from 5-aminouracil.. Talanta, 82 ((2)): (845-849). [PMID:20602979]
20. K K Upadhyay,Ajit Kumar. (2010-09-08) Pyrimidine based highly sensitive fluorescent receptor for Al3+ showing dual signalling mechanism.. Organic & biomolecular chemistry, 8 ((21)): (4892-4897). [PMID:20820652]
21. Akos Bányász,Szilvia Karpati,Yannick Mercier,Mar Reguero,Thomas Gustavsson,Dimitra Markovitsi,Roberto Improta. (2010-09-14) The peculiar spectral properties of amino-substituted uracils: a combined theoretical and experimental study.. The journal of physical chemistry. B, 114 ((39)): (12708-12719). [PMID:20831146]
22. Asmaa M Fahim,Mohamed S Elshikh,Noura M Darwish. (2019-07-11) Synthesis, Antitumor Activity, Molecular Docking and DFT Study of Novel Pyrimidiopyrazole Derivatives.. Current computer-aided drug design, 16 ((4)): (486-499). [PMID:31288728]

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所需的复溶浓度

货号 (SKU)	包装规格	是否现货
A119337-5g	5g	现货
A119337-25g	25g	现货
A119337-100g	100g	现货

5-氨基尿嘧啶

库存信息

库存信息

库存信息

基本描述

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器