基本描述

别名	腺苷-5'-单磷酸二钠盐 \| 5'-AMP二钠盐 \| 5'-O-磷酸腺苷二钠 \| 磷酸[(2R,3S,4R,5R)-5-(6-氨基-9H-嘌呤-9-基)-3,4-二羟基四氢呋喃-2-基]甲基钠
英文别名	Adenosine 5'-monophosphate disodium salt \| UNII-T1WZ11DSRN \| 5'-ADENYLIC ACID, SODIUM SALT (1:2) \| AMP disodium salt \| MFCD08689634 \| Adenosine 5'-monophosphate, disodium salt \| Adenosine 5'-monophosphoric acid disodium salt \| A884311 \| Disodium adenosine
规格或纯度	Moligand™, ≥99%
英文名称	5'-AMP-Na2
生化机理	核苷酸参与细胞能量转移的反应。充当AMP激活的蛋白激酶（AMPK）的激活剂。用作AMP-胸苷激酶，AMP脱氨酶和5'-核苷酸酶等酶的底物。
应用	A nucleotide involved in the reactions of cellular energy transfers.
储存温度	-20°C储存,充氩
运输条件	超低温冰袋运输
备注	如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍	Adenosine 5′-Monophosphate, Disodium Salt is a nucleotide that is widely distributed in nature. Adenosine 5′-Monophosphate, Disodium Salt is an activator of AMPK.A nucleotide involved in the reactions of cellular energy transfers. Adenosine 5′-Monophosphate, Disodium Salt is a nucleotide that is widely distributed in nature. Adenosine 5′-Monophosphate, Disodium Salt is an activator of AMPK. A nucleotide involved in the reactions of cellular energy transfers.
纯度	≥99%

名称和识别符

分子类型	小分子
IIUPAC Name	disodium;[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
INCHI	1S/C10H14N5O7P.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
InChi Key	QGXLVXZRPRRCRP-IDIVVRGQSA-L
Smiles	C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])[O-])O)O)N.[Na+].[Na+]
Isomeric SMILES	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])[O-])O)O)N.[Na+].[Na+]
关联CAS	13474-03-8
PubChem CID	20712
分子量	391.18

化学和物理性质

溶解性	Soluble in water (50 mg/ml), DMSO, and methanol.
密度	1.525
敏感性	对空气及湿度敏感
比旋光度	[α]20/D ?43±2°, c = 1% in 0.5 M Na2HPO4 (dry matter)
熔点	300 °C
分子量	391.190 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count	3
氢键受体数Hydrogen Bond Acceptor Count	11
可旋转键计数Rotatable Bond Count	3
精确质量Exact Mass	391.027 Da
单同位素质量Monoisotopic Mass	391.027 Da
拓扑极表面积Topological Polar Surface Area	192.000 Å²
重原子数Heavy Atom Count	25
形式电荷Formal Charge	0
复杂度Complexity	469.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	4
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	3

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批号(Lot Number)	证书类型	货号
A2203092	分析证书	A100357
A2203212	分析证书	A100357
A2203222	分析证书	A100357
F2530396	分析证书	A100357
F2530398	分析证书	A100357
F2530399	分析证书	A100357
D2409100	分析证书	A100357
D2409101	分析证书	A100357
F1918201	分析证书	A100357
G2222051	分析证书	A100357
G2222054	分析证书	A100357
G2222055	分析证书	A100357
G2222178	分析证书	A100357
J2431236	分析证书	A100357
B2418220	分析证书	A100357

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引用文献

1. Liu Yujie, Gao Ran, Liu Xingcen, Zheng Jinhua, Wu Xia. (2023) High-efficiency fluorescent coordination polymer nanoparticles co-doped with Ce3+/Tb3+ ions for curcumin detection. MICROCHIMICA ACTA, 190 (9): (1-11). [PMID:37587349] [10.1007/s00604-023-05933-6]
2. Pan Wang, Mengdei Zhou, Zhuangxin Wei, Lu Liu, Tao Cheng, Xiaohua Tian, Jianming Pan. (2023) Preparation of bowl-shaped polydopamine surface imprinted polymer composite adsorbent for specific separation of 2′-deoxyadenosine. CHINESE JOURNAL OF CHEMICAL ENGINEERING, 60 (69). [10.1016/j.cjche.2023.01.009]
3. Chujing Yang, Zhiwei Zhang, Jingqi Chen, Xinying Zhang, Yankai Dai, Xuyi Li, Yingying Chen, Jiaqiang Xu, Lingyan Feng. (2023) Multiple switchable circularly polarized luminescence from nucleotide/terbium(III) complexes. NEW JOURNAL OF CHEMISTRY, 47 (9): (4472-4477). [10.1039/D2NJ06145G]
4. Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan. (2022) Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, 302 (122048). [10.1016/j.seppur.2022.122048]
5. Xiao-Yan Cao, Yuan-Zhe Ni, Jing Li, Ling Li, Yi-Lin Zhao, Gui-Peng Yang. (2022) Sorption and distribution performance of organophosphorus compound (Adenosine 5′-monophosphate)on marine sediments. ENVIRONMENTAL POLLUTION, 311 (119993). [PMID:35995290] [10.1016/j.envpol.2022.119993]
6. Amjad Hussain Memon, Bin Wei, Saira Shams, Yucui Jiang, Mengzhao Jiao, Mingming Su, Hao Liang. (2022) Construction of robust bienzyme-mimicking nanocatalysts for dye degradation by self-assembly of hematin, metal ions, and nucleotides. Catalysis Science & Technology, 12 (9): (2846-2855). [10.1039/D1CY01125A]
7. Yucui Jiang, Saixing Liu, Qipeng Yuan, Hao Liang. (2021) Zr-based acid-stable nucleotide coordination polymers: An excellent platform for acidophilic enzymes immobilization. JOURNAL OF INORGANIC BIOCHEMISTRY, 216 (111338). [PMID:33445108] [10.1016/j.jinorgbio.2020.111338]
8. Xiaofang Jiang, Jing Hu, Yajun Zhang, Xiaoliang Zeng, Zhou Long. (2020) Fast synthesis of bimetallic metal-organic frameworks based on dielectric barrier discharge for analytical atomic spectrometry and ratiometric fluorescent sensing. MICROCHEMICAL JOURNAL, 159 (105417). [10.1016/j.microc.2020.105417]
9. Saira Shams, Waqas Ahmad, Amjad Hussain Memon, Yun Wei, Qipeng Yuan, Hao Liang. (2019) Facile synthesis of laccase mimic Cu/H3BTC MOF for efficient dye degradation and detection of phenolic pollutants. RSC Advances, 9 (70): (40845-40854). [PMID:35540072] [10.1039/C9RA07473B]
10. Ting Zou, You Han, Xinxue Li, Wei Li, Jinli Zhang, Yan Fu. (2019) Unexpected catalytic activity of Pd(II)-coordinated nucleotides in hydrogenation reduction. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 560 (344). [10.1016/j.colsurfa.2018.10.034]
11. Chunning Heng, Xin Zhou, Xiaoyan Zheng, Meiying Liu, Yuanqing Wen, Hongye Huang, Daidi Fan, Junfeng Hui, Xiaoyong Zhang, Yen Wei. (2018) Surface grafting of rare-earth ions doped hydroxyapatite nanorods (HAp:Ln(Eu/Tb)) with hydrophilic copolymers based on ligand exchange reaction: Biological imaging and cancer treatment. Materials Science & Engineering C-Materials for Biological Applications, 91 (556). [PMID:30033287] [10.1016/j.msec.2018.05.079]
12. Chunfang Li, Shuhui Jiang, Xinying Zhao, Hao Liang. (2017) Co-Immobilization of Enzymes and Magnetic Nanoparticles by Metal-Nucleotide Hydrogelnanofibers for Improving Stability and Recycling. MOLECULES, 22 (1): (179). [PMID:28125003] [10.3390/molecules22010179]
13. Hao Liang, Feifei Lin, Zijie Zhang, Biwu Liu, Shuhui Jiang, Qipeng Yuan, Juewen Liu. (2017) Multicopper Laccase Mimicking Nanozymes with Nucleotides as Ligands. ACS Applied Materials & Interfaces, 9 (2): (1352–1360). [PMID:28004568] [10.1021/acsami.6b15124]
14. Yihui Hu, Wenjing Guo, Yubin Ding, Hanjun Cheng, Hui Wei. (2016) Modulating luminescence of Tb3+ with biomolecules for sensing heparin and its contaminant OSCS. BIOSENSORS & BIOELECTRONICS, 86 (858). [PMID:27494809] [10.1016/j.bios.2016.07.085]
15. Hao Liang, Shuhui Jiang, Qipeng Yuan, Guofeng Li, Feng Wang, Zijie Zhang, Juewen Liu. (2016) Co-immobilization of multiple enzymes by metal coordinated nucleotide hydrogel nanofibers: improved stability and an enzyme cascade for glucose detection. Nanoscale, 8 (11): (6071-6078). [PMID:26932320] [10.1039/C5NR08734A]
16. Jian Sun, Bin Wang, Xue Zhao, Zong-Jun Li, Xiurong Yang. (2016) Fluorescent and Colorimetric Dual-Readout Assay for Inorganic Pyrophosphatase with Cu2+-Triggered Oxidation of o-Phenylenediamine. ANALYTICAL CHEMISTRY, 88 (2): (1355–1361). [PMID:26703206] [10.1021/acs.analchem.5b03848]

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货号 (SKU)	包装规格	是否现货
A100357-5g	5g	现货
A100357-25g	25g	现货
A100357-100g	100g	现货
A100357-500g	500g	现货

5'-腺嘌呤核苷酸二钠盐

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基本描述

名称和识别符

化学和物理性质

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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