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Varlilumab (anti-TNFRSF7) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD27, >95%, high purity, Human IgG1, AGONIST of CD27 antigen agonist, AGONIST of CD27 antigen agonist

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Rhesus monkey
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170646
Grouped product items
SKU Size
Availability
Price Qty
Ab170646-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$149.90
Ab170646-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$747.90
Ab170646-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$2,487.90
Ab170646-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,888.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Varlilumab (anti-TNFRSF7) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD27, >95%, high purity, Human IgG1, AGONIST of CD27 antigen agonist
Synonyms CD 27 antibody | CD27 antibody | CD27 antigen antibody | CD27 molecule antibody | CD27_HUMAN antibody | CD27L receptor antibody | LPFS2 antibody | MGC20393 antibody | OTTHUMP00000238557 antibody | S152 antibody | T cell activation antigen CD27 antibody |
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD27
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type AGONIST
Mechanism of action AGONIST of CD27 antigen agonist
Product Description

Varlilumab is a first-of-its-kind human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity.
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 27.0 kDa (Light Chain) & 51.9 kDa (Heavy Chain), under reducing conditions; 180.0 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1393344-72-3

Associated Targets(Human)

CD27 Tbio CD27 antigen (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Varlilumab (anti-TNFRSF7) (Ab170646) - Flow Cytometry
Flow Cytometry analysis of PBMC cells labelling TNFRSF7 (red) with Varlilumab (anti-TNFRSF7) (Ab170646). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Varlilumab (anti-TNFRSF7) (Ab170646) - SEC
The purity of Varlilumab (anti-TNFRSF7) (Ab170646) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F0900986 Certificate of Analysis Jun 24, 2025 Ab170646
ZJ23F0900987 Certificate of Analysis Sep 11, 2023 Ab170646

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