Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab170646-100μg
|
100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$149.90
|
|
|
Ab170646-1mg
|
1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$747.90
|
|
|
Ab170646-5mg
|
5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$2,487.90
|
|
|
Ab170646-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$3,888.90
|
|
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Varlilumab (anti-TNFRSF7) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD27, >95%, high purity, Human IgG1, AGONIST of CD27 antigen agonist |
|---|---|
| Synonyms | CD 27 antibody | CD27 antibody | CD27 antigen antibody | CD27 molecule antibody | CD27_HUMAN antibody | CD27L receptor antibody | LPFS2 antibody | MGC20393 antibody | OTTHUMP00000238557 antibody | S152 antibody | T cell activation antigen CD27 antibody | |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CD27 |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | AGONIST |
| Mechanism of action | AGONIST of CD27 antigen agonist |
| Product Description |
Varlilumab is a first-of-its-kind human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity. |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG1 |
| Light Chain Type | kappa |
| SDS-PAGE | 27.0 kDa (Light Chain) & 51.9 kDa (Heavy Chain), under reducing conditions; 180.0 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1393344-72-3 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Varlilumab (anti-TNFRSF7) (Ab170646) - Flow Cytometry
Flow Cytometry analysis of PBMC cells labelling TNFRSF7 (red) with Varlilumab (anti-TNFRSF7) (Ab170646). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Varlilumab (anti-TNFRSF7) (Ab170646) - SEC
The purity of Varlilumab (anti-TNFRSF7) (Ab170646) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 24, 2025 | Ab170646 | |
| Certificate of Analysis | Sep 11, 2023 | Ab170646 |