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Tomaralimab (anti-TLR2) - Primary antibody, specific to TLR2, >95%, high purity, Human IgG4SP, ANTAGONIST of Toll-like receptor 2 antagonist, ANTAGONIST of Toll-like receptor 2 antagonist

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab176102
Grouped product items
SKU Size
Availability
Price Qty
Ab176102-100μg
100μg
10
$59.90
Ab176102-1mg
1mg
4
$289.90
Ab176102-5mg
5mg
1
$749.90
Ab176102-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,189.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Tomaralimab (anti-TLR2) - Primary antibody, specific to TLR2, >95%, high purity, Human IgG4SP, ANTAGONIST of Toll-like receptor 2 antagonist
Synonyms CD282 antibody | CD282 antigen antibody | TIL 4 antibody | TIL4 antibody | TLR 2 antibody | TLR2 antibody | TLR2_HUMAN antibody | Toll like receptor 2 antibody | Toll like receptor 2 precursor antibody | Toll-like receptor 2 antibody | Toll/interleukin 1
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity TLR2
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type ANTAGONIST
Mechanism of action ANTAGONIST of Toll-like receptor 2 antagonist
Product Description

Tomaralimab (anti-TLR2) is a humanised anti-TLR2 IgG4 monoclonal antibody. Tomaralimab (anti-TLR2) has the potential for the research of Myelodysplastic Syndromes (MDS).
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 27.2 kDa (Light Chain) & 49.1 kDa (Heavy Chain), under reducing conditions; 166.8 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1449294-76-1

Associated Targets(Human)

TLR2 Tchem Toll-like receptor 2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
TLR2 Tchem Toll-like receptor 2 (975 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TLR2 Tchem TLR2/TLR6 (50 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Tomaralimab (anti-TLR2) (Ab176102) - Flow Cytometry
Flow Cytometry analysis of THP-1 cells labelling TLR2 (red) with Tomaralimab (anti-TLR2) (Ab176102). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Tomaralimab (anti-TLR2) (Ab176102) - SEC
The purity of Tomaralimab (anti-TLR2) (Ab176102) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404825 Certificate of Analysis Apr 24, 2024 Ab176102
ZJ24F0404824 Certificate of Analysis Apr 24, 2024 Ab176102
ZJ24F0404823 Certificate of Analysis Apr 24, 2024 Ab176102

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