Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab176102-100μg
|
100μg |
10
|
$59.90
|
|
|
Ab176102-1mg
|
1mg |
4
|
$289.90
|
|
|
Ab176102-5mg
|
5mg |
1
|
$749.90
|
|
|
Ab176102-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,189.90
|
|
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Tomaralimab (anti-TLR2) - Primary antibody, specific to TLR2, >95%, high purity, Human IgG4SP, ANTAGONIST of Toll-like receptor 2 antagonist |
|---|---|
| Synonyms | CD282 antibody | CD282 antigen antibody | TIL 4 antibody | TIL4 antibody | TLR 2 antibody | TLR2 antibody | TLR2_HUMAN antibody | Toll like receptor 2 antibody | Toll like receptor 2 precursor antibody | Toll-like receptor 2 antibody | Toll/interleukin 1 |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | TLR2 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | ANTAGONIST |
| Mechanism of action | ANTAGONIST of Toll-like receptor 2 antagonist |
| Product Description |
Tomaralimab (anti-TLR2) is a humanised anti-TLR2 IgG4 monoclonal antibody. Tomaralimab (anti-TLR2) has the potential for the research of Myelodysplastic Syndromes (MDS). |
| Isotype | Human IgG4SP |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 27.2 kDa (Light Chain) & 49.1 kDa (Heavy Chain), under reducing conditions; 166.8 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1449294-76-1 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Tomaralimab (anti-TLR2) (Ab176102) - Flow Cytometry
Flow Cytometry analysis of THP-1 cells labelling TLR2 (red) with Tomaralimab (anti-TLR2) (Ab176102). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Tomaralimab (anti-TLR2) (Ab176102) - SEC
The purity of Tomaralimab (anti-TLR2) (Ab176102) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 24, 2024 | Ab176102 | |
| Certificate of Analysis | Apr 24, 2024 | Ab176102 | |
| Certificate of Analysis | Apr 24, 2024 | Ab176102 |