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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab191919-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab191919-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$519.90
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Ab191919-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,299.90
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Ab191919-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,079.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG4SP; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | TNX-832 (anti-Tissue Factor) - Primary antibody, specific to F3, Human IgG4SP |
|---|---|
| Synonyms | CD142 antibodyCD142 antigen antibody | Coagulation factor III (thromboplastin tissue factor) antibody | Coagulation factor III antibody | F3 antibody | FLJ17960 antibody | TF antibody | TF_HUMAN antibody | TFA antibody | Thromboplastin antibody | Tissue f |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagat |
| Host species | Human |
| Specificity | F3 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
TNX-832 (anti-Tissue Factor) is humanized form of an antibody capable of targeting tissue factor (coagulation factor F3). It is useful in treating conditions, such as tumor progression.
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| Isotype | Human IgG4SP |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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TNX-832 (anti-Tissue Factor) (Ab191919) - ELISA
Immobilized Recombinant Human Tissue factor / CD142, Fc Tag protein at 2.0 μg/mL can bind TNX-832 (anti-Tissue Factor) (Ab191919) with the EC50 of 23.10 ng/mL.
TNX-832 (anti-Tissue Factor) (Ab191919) - SEC
The purity of TNX-832 (anti-Tissue Factor) (Ab191919) is more than 95% verified by HPLC.
Starting at $69.90