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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
S414640-5mg
|
5mg |
3
|
$83.90
|
|
|
S414640-25mg
|
25mg |
2
|
$275.90
|
|
|
S414640-100mg
|
100mg |
2
|
$893.90
|
|
| Synonyms | AKOS037645436 | ompenaclid [INN] | N-octadecanoylsphing-4-enine-1-phosphocholine | (2S,3R,4E)-3-hydroxy-2-(stearoylamino)octadec-4-en-1-yl 2-(trimethylammonio)ethyl phosphate | SCHEMBL14889266 | CS-0621186 | SM d36:1 | 3,5-DIOXA-8-AZA-4-PHOSPHAHEXACOSAN-1 |
|---|---|
| Specifications & Purity | ≥95%, natural bovine mixture |
| Biochemical and Physiological Mechanisms | Sphingomyelin is the second most abundant lipid and major sphingolipid component of HDL and the plasma membrane. It forms cholesterol-enriched lipid rafts. It has a key role in the availability of plasma membrane-free cholesterol. |
| Storage Temp | Store at -20°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
Sphingomyelin (SM) is a principal sphingolipid in mammalian cell membranes. Its biological functions have been studied. Application: Sphingomyelin is suitable for use: |
| pKa | pKa: 1.24 |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Smiles | CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)([O-])OCC[N+](C)(C)C)[C@@H](/C=C/CCCCCCCCCCCCC)O |
|---|---|
| Isomeric SMILES | CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)([O-])OCC[N+](C)(C)C)[C@@H](/C=C/CCCCCCCCCCCCC)O |
| WGK Germany | 3 |
| PubChem CID | 6453725 |
| Molecular Weight | 731.08 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Feb 07, 2025 | S414640 | |
| Certificate of Analysis | Feb 07, 2025 | S414640 | |
| Certificate of Analysis | Jan 16, 2024 | S414640 | |
| Certificate of Analysis | Jan 16, 2024 | S414640 | |
| Certificate of Analysis | Jan 16, 2024 | S414640 | |
| Certificate of Analysis | Jun 20, 2022 | S414640 | |
| Certificate of Analysis | Jun 20, 2022 | S414640 | |
| Certificate of Analysis | Jun 20, 2022 | S414640 | |
| Certificate of Analysis | Jun 20, 2022 | S414640 |
| Solubility | Ethanol: 10 mg/ml |
|---|---|
| Molecular Weight | 731.100 g/mol |
| XLogP3 | 13.400 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 38 |
| Exact Mass | 730.599 Da |
| Monoisotopic Mass | 730.599 Da |
| Topological Polar Surface Area | 108.000 Ų |
| Heavy Atom Count | 50 |
| Formal Charge | 0 |
| Complexity | 826.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |
Starting at $120.90
| 1. Qiangqiang Li, Gang Chen, Dan Zhu, Wenwen Zhang, Suzhen Qi, Xiaofeng Xue, Kai Wang, Liming Wu. (2022) Effects of dietary phosphatidylcholine and sphingomyelin on DSS-induced colitis by regulating metabolism and gut microbiota in mice. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 105 (109004). |
| 2. Wei Wei, Jin Cheng, Jie Yang, Chen Chen, Qingzhe Jin, Jie Song, Xingguo Wang. (2021) Phospholipid composition and fat globule structure change during low temperature storage of human milk. LWT-FOOD SCIENCE AND TECHNOLOGY, 150 (112050). |
| 3. Chen Fangquan, Tang Hu, Lin Junhao, Xiang Limin, Lu Yanjiao, Kang Rui, Tang Daolin, Liu Jiao. (2024) Macropinocytosis inhibits alkaliptosis in pancreatic cancer cells through fatty acid uptake. CARCINOGENESIS, |
| 4. Yang Yang, Xin Zhang, Jin Yang, Ziyan Wu, Junpeng Li, Ruilong Song, Chuang Meng, Guoqiang Zhu. (2025) N-(3-Oxododecanoyl)-Homoserine Lactone Induces Intestinal Barrier Damage in Piglets via the Lipid Raft-Mediated Apoptosis Pathway. Veterinary Sciences, 12 (3): (233). |
| 5. Zhirong Li, Lulu Zhang, Zhanzhong Wang, Xiongli Kang, Huiying Jin, Wenjie Zhao, Jun Zhang, Haiquan Su. (2024) Quantification of Phosphatidylserine Molecules on the Surface of Individual Cells Using Single-Molecule Force Spectroscopy. ANALYTICAL CHEMISTRY, 96 (2): (676-684). |