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Sphingomyelin - ≥95%(TLC),from chicken egg yolk, high purity , CAS No.85187-10-6

    Grade & Purity:
  • ≥95%(TLC)
  • from chicken egg yolk
In stock
Item Number
S477613
Grouped product items
SKU Size
Availability
Price Qty
S477613-10mg
10mg
1
$120.90
S477613-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$480.90
View related series
Eukaryotic sphingolipid (1)

Basic Description

Synonyms N-Acyl-4-sphingenyl-1-O-phosphorylcholine | N-Acyl-D-sphingosine-1-phosphocholine
Specifications & Purity ≥95%(TLC), from chicken egg yolk
Biochemical and Physiological Mechanisms Sphingomyelin is the second most abundant lipid and major sphingolipid component of HDL and the plasma membrane. It forms cholesterol-enriched lipid rafts. It has a key role in the availability of plasma membrane-free cholesterol.
Storage Temp Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Contains primarily palmitic acid.
Sphingomyelin (SM) is a principal sphingolipid in mammalian cell membranes. Its biological functions have been studied.
Sphingomyelin is suitable for use:
in the preparation of standard during the enzymatic measurement of plasma sphingomyelin levels;to study the binding of Vascular Anticoagulant α (VAC α) to planar phospholipid bilayers;to perform fluorescence polarization of PC16 (N-[α-N-palmitoyl-ε-N-(4-nitrobenz-2-oxa-1,3-diazole)-L-lysine]-2-aminoethanol-N- (trimethylaminoethanol) phosphate) in dispersions of co-sonicated lecithin and sphingomyelin; for reconstitution of viral ion channel protein M2 into liposomes as a standard sample to define spectral fingerproint using Time-of-flight secondary ion mass spectrometry (ToF-SIMS);to evaluate the contribution of various phospholipids to the formation of foam in the amniotic fluid

Product Properties

pKa pKa: 1.24

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Smiles CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)([O-])OCC[N+](C)(C)C)[C@@H](/C=C/CCCCCCCCCCCCC)O
Isomeric SMILES CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)([O-])OCC[N+](C)(C)C)[C@@H](/C=C/CCCCCCCCCCCCC)O
WGK Germany 3
PubChem CID 6453725
Molecular Weight 731.08

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number Certificate Type Date Item
C2520434 Certificate of Analysis May 13, 2024 S477613
C2520435 Certificate of Analysis May 13, 2024 S477613
C2520433 Certificate of Analysis May 13, 2024 S477613
H2415527 Certificate of Analysis Apr 29, 2024 S477613
H2415528 Certificate of Analysis Apr 29, 2024 S477613
H2415526 Certificate of Analysis Apr 29, 2024 S477613

Chemical and Physical Properties

Sensitivity Air, light and moisture sensitive
Molecular Weight 731.100 g/mol
XLogP3 13.400
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 38
Exact Mass 730.599 Da
Monoisotopic Mass 730.599 Da
Topological Polar Surface Area 108.000 Ų
Heavy Atom Count 50
Formal Charge 0
Complexity 826.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 2
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 1
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 1
Covalently-Bonded Unit Count 1

Citations of This Product

1. Qiangqiang Li, Gang Chen, Dan Zhu, Wenwen Zhang, Suzhen Qi, Xiaofeng Xue, Kai Wang, Liming Wu.  (2022)  Effects of dietary phosphatidylcholine and sphingomyelin on DSS-induced colitis by regulating metabolism and gut microbiota in mice.  JOURNAL OF NUTRITIONAL BIOCHEMISTRY,  105  (109004). 
2. Wei Wei, Jin Cheng, Jie Yang, Chen Chen, Qingzhe Jin, Jie Song, Xingguo Wang.  (2021)  Phospholipid composition and fat globule structure change during low temperature storage of human milk.  LWT-FOOD SCIENCE AND TECHNOLOGY,  150  (112050). 
3. Chen Fangquan, Tang Hu, Lin Junhao, Xiang Limin, Lu Yanjiao, Kang Rui, Tang Daolin, Liu Jiao.  (2024)  Macropinocytosis inhibits alkaliptosis in pancreatic cancer cells through fatty acid uptake.  CARCINOGENESIS,     
4. Yang Yang, Xin Zhang, Jin Yang, Ziyan Wu, Junpeng Li, Ruilong Song, Chuang Meng, Guoqiang Zhu.  (2025)  N-(3-Oxododecanoyl)-Homoserine Lactone Induces Intestinal Barrier Damage in Piglets via the Lipid Raft-Mediated Apoptosis Pathway.  Veterinary Sciences,  12  (3): (233). 
5. Zhirong Li, Lulu Zhang, Zhanzhong Wang, Xiongli Kang, Huiying Jin, Wenjie Zhao, Jun Zhang, Haiquan Su.  (2024)  Quantification of Phosphatidylserine Molecules on the Surface of Individual Cells Using Single-Molecule Force Spectroscopy.  ANALYTICAL CHEMISTRY,  96  (2): (676-684). 

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