Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab183093-100μg
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100μg |
10
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$69.90
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Ab183093-1mg
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1mg |
4
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$329.90
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Ab183093-5mg
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5mg |
1
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$689.90
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Ab183093-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,099.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Sibrotuzumab (anti-FAP) - Primary antibody, specific to FAP, Human IgG1, BINDING AGENT of Fibroblast activation protein alpha binding agent |
|---|---|
| Synonyms | 170 kDa melanoma membrane-bound gelatinase antibody | Dipeptidyl peptidase FAP antibody | DPPIV antibody | FAP antibody | FAPA antibody | FAPalpha antibody | Fibroblast activation protein alpha antibody | Gelatine degradation protease FAP antibody | Integ |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | FAP |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | BINDING AGENT |
| Mechanism of action | BINDING AGENT of Fibroblast activation protein alpha binding agent |
| Product Description |
Sibrotuzumab (anti-FAP) is a humanized IgG1 monoclonal antibody targets fibroblast activation protein (FAP). Sibrotuzumab (anti-FAP) can be used for the research of colorectal cancer and non-small cell lung cancer (NSCLC). |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 148.66 kDa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 216669-97-5 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Sibrotuzumab (anti-FAP) (Ab183093) - SEC
The purity of Sibrotuzumab (anti-FAP) (Ab183093) is more than 95% verified by HPLC.
Sibrotuzumab (anti-FAP) (Ab183093) - ELISA
Immobilized Human FAP-his tag at 2.0 μg/mL can bind Sibrotuzumab (anti-FAP) (Ab183093) with the EC₅₀ of 2.91 ng/mL.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | May 16, 2024 | Ab183093 | |
| Certificate of Analysis | May 16, 2024 | Ab183093 | |
| Certificate of Analysis | May 16, 2024 | Ab183093 |