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Sanofi patent anti-PAI-1 (anti-SERPINE1) - Primary antibody, specific to SERPINE1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab209768
Grouped product items
SKU Size
Availability
Price Qty
Ab209768-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab209768-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$509.90
Ab209768-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,399.90
Ab209768-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Sanofi patent anti-PAI-1 (anti-SERPINE1) - Primary antibody, specific to SERPINE1
Synonyms Clade E antibody | Endothelial plasminogen activator inhibitor antibody | Nexin antibody | Nexin plasminogen activator inhibitor type 1 antibody | PAI 1 antibody | PAI antibody | PAI-1 antibody | PAI1_HUMAN antibody | PLANH1 antibody | Plasminogen activat
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. Post-translational: Inactivated by proteolytic attack of the
Host species Human
Specificity SERPINE1
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Sanofi patent anti-PAI-1 (anti-SERPINE1) is a monoclonal antibody that specifically binds to Plasminogen Activator Inhibitor Type-1 (PAI-1, SERPINE1) with the potential to be used in cardiovascular diseases.

Product Properties

Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

SERPINE1 Tchem Plasminogen activator inhibitor 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Sanofi patent anti-PAI-1 (anti-SERPINE1) (Ab209768) - ELISA
Immobilized Recombinant  Human Serpin E1/PAI-1 protein (rp181294) at 1.0 μg/mL can bind Sanofi patent anti-PAI-1 (anti-SERPINE1) (Ab209768), with the EC50 of 38.78 ng/mL.

Sanofi patent anti-PAI-1 (anti-SERPINE1) (Ab209768) - ELISA
Immobilized Recombinant Hu/cyno- GIPR-ECD-His protein at 2.0 μg/mL can bind Sanofi patent anti-PAI-1 (anti-SERPINE1) (Ab209768) with the EC50 of 9.981 ng/mL.

Sanofi patent anti-PAI-1 (anti-SERPINE1) (Ab209768) - SEC
The purity of Sanofi patent anti-PAI-1 (anti-SERPINE1) (Ab209768) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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