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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab209768-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab209768-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$509.90
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Ab209768-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,399.90
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Ab209768-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,299.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | Sanofi patent anti-PAI-1 (anti-SERPINE1) - Primary antibody, specific to SERPINE1 |
|---|---|
| Synonyms | Clade E antibody | Endothelial plasminogen activator inhibitor antibody | Nexin antibody | Nexin plasminogen activator inhibitor type 1 antibody | PAI 1 antibody | PAI antibody | PAI-1 antibody | PAI1_HUMAN antibody | PLANH1 antibody | Plasminogen activat |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. Post-translational: Inactivated by proteolytic attack of the |
| Host species | Human |
| Specificity | SERPINE1 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Sanofi patent anti-PAI-1 (anti-SERPINE1) is a monoclonal antibody that specifically binds to Plasminogen Activator Inhibitor Type-1 (PAI-1, SERPINE1) with the potential to be used in cardiovascular diseases. |
| Light Chain Type | kappa |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Sanofi patent anti-PAI-1 (anti-SERPINE1) (Ab209768) - ELISA
Immobilized Recombinant Human Serpin E1/PAI-1 protein (rp181294) at 1.0 μg/mL can bind Sanofi patent anti-PAI-1 (anti-SERPINE1) (Ab209768), with the EC50 of 38.78 ng/mL.
Sanofi patent anti-PAI-1 (anti-SERPINE1) (Ab209768) - ELISA
Immobilized Recombinant Hu/cyno- GIPR-ECD-His protein at 2.0 μg/mL can bind Sanofi patent anti-PAI-1 (anti-SERPINE1) (Ab209768) with the EC50 of 9.981 ng/mL.
Sanofi patent anti-PAI-1 (anti-SERPINE1) (Ab209768) - SEC
The purity of Sanofi patent anti-PAI-1 (anti-SERPINE1) (Ab209768) is more than 95% verified by HPLC.
Starting at $139.90
Starting at $139.90