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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab209857-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab209857-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$519.90
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Ab209857-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,299.90
|
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Ab209857-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,079.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG2SA; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | Rinat patent anti-TrkB (anti-TrkB) - Primary antibody, specific to NTRK2, Human IgG2SA |
|---|---|
| Synonyms | AI848316 antibody | BDNF tropomyosine receptor kinase B antibody | BDNF/NT 3 growth factors receptor antibody | BDNF/NT-3 growth factors receptor antibody | Brain derived neurotrophic factor receptor antibody | C030027L06Rik antibody | EC 2.7.10.1 antibod |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrate |
| Host species | Human |
| Specificity | NTRK2 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Rinat patent anti-TrkB (anti-TrkB) is an antibody targeting TrkB. It is used to improve nerve function, including treatment of peripheral neuropathies. |
| Isotype | Human IgG2SA |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 146.38 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Rinat patent anti-TrkB (anti-TrkB) (Ab209857) - ELISA
Immobilized Recombinant Human TrkB protein (rp181612) at 1.0 μg/mL can bind Rinat patent anti-TrkB (anti-TrkB) (Ab209857) with the EC50 of 34.2 ng/mL.
Rinat patent anti-TrkB (anti-TrkB) (Ab209857) - Flow Cytometry
Flow Cytometry analysis of HuTRKB-[luc2P/NFAT-RE/Hygro]-CHO-K1-A14 cells labelling SLITRK6 at 1×105 cell/well can bind Rinat patent anti-TrkB (anti-TrkB) (Ab209857), with the EC50 is 0.342 μg/mL.
Rinat patent anti-TrkB (anti-TrkB) (Ab209857) - SEC
The purity of Rinat patent anti-TrkB (anti-TrkB) (Ab209857) is more than 95% verified by HPLC.