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Regeneron patent anti-TIE-2 (anti-TIE2) - Primary antibody, specific to TEK

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse,Rat
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab209774
Grouped product items
SKU Size
Availability
Price Qty
Ab209774-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab209774-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$509.90
Ab209774-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,399.90
Ab209774-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG4SP; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Regeneron patent anti-TIE-2 (anti-TIE2) - Primary antibody, specific to TEK
Synonyms Angiopoietin 1 receptor antibody | Angiopoietin-1 receptor antibody | CD202b antibody | CD202b antigen antibody | Endothelial tyrosine kinase antibody | Endothelium specific receptor tyrosine kinase 2 antibody | hTIE 2 antibody | hTIE2 antibody | Hyk anti
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Tyrosine-protein kinase that acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maint
Host species Human
Specificity TEK
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Regeneron patent anti-TIE-2 (anti-TIE2) is a fully human monoclonal antibody that binds to human Tie2 and blocks the interaction between Tie2 or Tie2 ligands (angiopoietin). It has the potential to treat angiogenesis disorders.

Product Properties

Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

TEK Tclin Angiopoietin-1 receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Regeneron patent anti-TIE-2 (anti-TIE2) (Ab209774) - ELISA
Immobilized Recombinant HUTIE2- ECD-gsvo-HUFC protein at 2.0 μg/mL can bind Regeneron patent anti-TIE-2 (anti-TIE2) (Ab209774), with the EC50 of 503.5 ng/mL.

Regeneron patent anti-TIE-2 (anti-TIE2) (Ab209774) - SEC
The purity of Regeneron patent anti-TIE-2 (anti-TIE2) (Ab209774) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

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