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Recombinant Human RANK Protein, >98%(SDS-PAGE), high purity

  • Expression System: E.coli
  • Accession #: Q9Y6Q6
  • Protein Tag: No tag
  • Bioactivity: Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit sRANK Ligand induced nuclear factor kappa B(NFkappaB) in RAW 264.7 cells is less than 50 ng/ml, corresponding to a specific activity of > 2.0 × 104 IU/mg in the presence of 15 ng/ml of recombinant sRANK Ligand.
  • Endotoxin Concentration: <0.1 EU/μg
In stock
Item Number
rp150851
Grouped product items
SKU Size
Availability
Price Qty
rp150851-10μg
10μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$59.90
rp150851-50μg
50μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$139.90
rp150851-100μg
100μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$209.90
rp150851-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,499.90

Animal Free, >98%(SDS-PAGE), Active, E. coli, No tag, 29-202 aa

Basic Description

Product Name Recombinant Human RANK Protein, >98%(SDS-PAGE), high purity
Synonyms CD 265 | CD265 | FEO | LOH18CR1 | Loss of heterozygosity 18 chromosomal region 1 | mRANK | ODFR | OFE | OPTB7 | Osteoclast differentiation factor receptor | OSTS | Paget disease of bone 2 | PDB 2 | PDB2 | RANK | Receptor activator of NF KB | Receptor acti
Grade ActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free, High Performance
Product Description

Purity
>98% SDS-PAGE.
Function
Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells.

Specifications & Purity ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥98%(SDS-PAGE)
Purity >98%(SDS-PAGE)
Bioactivity Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit sRANK Ligand induced nuclear factor kappa B(NFkappaB) in RAW 264.7 cells is less than 50 ng/ml, corresponding to a specific activity of > 2.0 × 104 IU/mg in the presence of 15 ng/ml of recombinant sRANK Ligand.
Endotoxin Concentration <0.1 EU/μg
Expression System E.coli
Species Human
Amino Acids 29-202 aa
Sequence QIAPPCTSEK HYEHLGRCCN KCEPGKYMSS KCTTTSDSVC LPCGPDEYLD SWNEEDKCLL HKVCDTGKAL VAVVAGNSTT PRRCACTAGY HWSQDCECCR RNTECAPGLG AQHPLQLNKD TVCKPCLAGY FSDAFSSTDK CRPWTNCTFL GKRVEHHGTE KSDAVCSSSL PARK
Protein Tag No tag
Accession # Q9Y6Q6
Predicted molecular weight 19.1 kDa
SDS-PAGE 20.5 kDa, under reducing conditions; 18.2 kDa, under non-reducing conditions.

Storage and Shipping

Shape Lyophilized
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 2-8 ℃ for one month. Aliquot and store at -80 ℃ for 12 months.Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Images

Recombinant Human RANK protein (rp150851) - SDS-PAGE
Recombinant Human RANK protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a single band at 20.5 kDa under reducing conditions and 18.2 kDa under non-reducing conditions.

Recombinant Human RANK protein (rp150851) - Protein Bioactivity
Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to inhibit RANK Ligand induced nuclear factor kappa B(NFkappaB) in RAW 264.7 cells is less than 50 ng/mL, corresponding to a specific activity of > 2.0 × 10⁴ IU/mg in the presence of 15 ng/mL of recombinant RANK Ligand.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ23F0700627 Certificate of Analysis Jul 21, 2023 rp150851
ZJ23F0700625 Certificate of Analysis Jul 20, 2023 rp150851
ZJ23F0700626 Certificate of Analysis Jul 20, 2023 rp150851

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