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| SKU | Size | Availability |
Price | Qty |
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rp166066-GMP-50μg
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50μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$469.90
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rp166066-GMP-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$3,759.90
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GMP, ≥97% (SDS-PAGE&SEC-HPLC), Active, E.coli, No tag, 21-153 aa (C145S)
| Product Name | Recombinant Human IL-2 GMP Protein |
|---|---|
| Synonyms | Interleukin 2 | Aldesleukin | IL2 | IL-2 | lymphokine | interleukin-2 | involved in regulation of T-cell clonal expansion | Proleukin | T cell growth factor | T-cell growth factor | TCGF |
| Grade | ActiBioPure™, Animal Free, Bioactive, Carrier Free, GMP, High Performance |
| Specifications & Purity | Animal Free, Carrier Free, GMP, Bioactive, High performance, ActiBioPure™, ≥97%(SDS-PAGE&SEC-HPLC) |
| Biochemical and Physiological Mechanisms | Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance. Binds to a receptor complex composed of either th |
| Bioactivity | Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.0300-0.250 ng/mL. The specific activity of recombinant human IL-2 is >5.00 x 10^6 IU/mg, which is calibrated against the human IL-2 WHO International Standard (NIBSC code: 86/500). |
| Endotoxin Concentration | <0.01 EU/μg |
| Expression System | E. coli |
| Amino Acids | 21-153 aa (C145S) |
| Sequence | MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITSCQSIISTLT |
| Protein Tag | No tag |
| N-terminal Sequence | Met-Ala21-Pro-Thr-Ser-Ser-Ser-Thr-Lys-Lys & Ala21-Pro-Thr-Ser-Ser-Ser-Thr-Lys-Lys-Thr |
| Accession # | P60568 |
| Predicted molecular weight | 15.5 kDa |
| SDS-PAGE | 13 kDa under reducing conditions. |
| Reconstitution | Reconstitute at 500 μg/mL in sterile deionized water. |
|---|---|
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | A minimum of 12 months when stored at ≤ -20 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, ≤ -20 ℃ under sterile conditions after reconstitution. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycl |
Starting at $59.90