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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab209881-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab209881-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$509.90
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Ab209881-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,399.90
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Ab209881-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,299.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | R707 (anti-CCR7) - Primary antibody, specific to CCR7 |
|---|---|
| Synonyms | BLR 2 antibody | BLR2 antibody | C C chemokine receptor type 7 antibody | C C CKR 7 antibody | C-C chemokine receptor type 7 antibody | Anti-CCR7 / CD197 antibody | MIP-3 beta receptor | lymphocyte-specific G protein-coupled peptide receptor | EVI1 | Epst |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. |
| Host species | Human |
| Specificity | CCR7 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
R707 (anti-CCR7) is a fully human antibody targeting CCR7 signaling and function. It exhibits the potential to prevent acute graft-versus-host disease (aGVHD). |
| Light Chain Type | kappa |
|---|---|
| SDS-PAGE | 145.36 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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R707 (anti-CCR7) (Ab209881) - Flow Cytometry:
Flow Cytometry analysis of huCCR7-CHO-K1 cells labelling CCR7 with R707 (anti-CCR7) (Ab209881) at 1×105 cell/well, with the EC₅₀ is 0.29 μg/mL.
R707 (anti-CCR7) (Ab209881) - SEC
The purity of R707 (anti-CCR7) (Ab209881) is more than 95% verified by HPLC.
Starting at $49.90
Starting at $49.90