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Pyridoxal hydrochloride - 99%, high purity , CAS No.65-22-5
Basic Description
Synonyms
3-Hydroxy-5-hydroxymethyl-2-methylisonicotinaldehyde hydrochloride | P0559 | 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride | 3-Hydroxy-5-(hydroxymethyl)-2-methyl-isonicotinaldehyde hydrochloride | 3-Hydroxy-5-(hydroxymethyl)-2-methy
Specifications & Purity
≥99%
Biochemical and Physiological Mechanisms
Pyridoxal hydrochloride interacts with cysteine of cathepsins and inhibits their activity. It elicits protective function in cornu Ammonis (CA) 1 neurons during ischemia.Pyridoxal hydrochloride is an endogenous metabolite.
Storage Temp
Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description
Pyridoxal hydrochloride is used in labeling of amino acids for their detection. It finds application in neurotransmitters, sphingolipids and aminolevulinic acid. It is also used as a nutritional agent. It is also applied in research studies like biochemical, drugs and in media supplements.
Taxonomic Classification
Kingdom
Organic compounds
Superclass
Organoheterocyclic compounds
Class
Pyridines and derivatives
Subclass
Pyridine carboxaldehydes
Intermediate Tree Nodes
Not available
Direct Parent
Pyridoxals and derivatives
Alternative Parents
Methylpyridines Hydroxypyridines Aryl-aldehydes Vinylogous acids Heteroaromatic compounds Azacyclic compounds Primary alcohols Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrochlorides Hydrocarbon derivatives Aromatic alcohols
Molecular Framework
Aromatic heteromonocyclic compounds
Substituents
Pyridoxal - Aryl-aldehyde - Methylpyridine - Hydroxypyridine - Vinylogous acid - Heteroaromatic compound - Azacycle - Alcohol - Hydrocarbon derivative - Organic oxide - Hydrochloride - Organopnictogen compound - Organic oxygen compound - Aromatic alcohol - Organic nitrogen compound - Primary alcohol - Organooxygen compound - Organonitrogen compound - Aldehyde - Aromatic heteromonocyclic compound
Description
This compound belongs to the class of organic compounds known as pyridoxals and derivatives. These are compounds containing a pyridoxal moiety, which consists of a pyridine ring substituted at positions 2,3,4, and 5 by a methyl group, a hydroxyl group, a carbaldehyde group, and a hydroxymethyl group, respectively.
External Descriptors
Not available
Data sources
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
Mechanism of Action
Action Type
target ID
Target Name
Target Type
Target Organism
Binding Site Name
References
Names and Identifiers
IUPAC Name
3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde;hydrochloride
INCHI
InChI=1S/C8H9NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,4,10,12H,3H2,1H3;1H
InChIKey
FCHXJFJNDJXENQ-UHFFFAOYSA-N
Smiles
CC1=NC=C(C(=C1O)C=O)CO.Cl
Isomeric SMILES
CC1=NC=C(C(=C1O)C=O)CO.Cl
WGK Germany
2
RTECS
UV1225000
Molecular Weight
203.62
Beilstein
3656994
Reaxy-Rn
3656994
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3656994&ln=
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
Sensitivity
Light Sensitive,Air Sensitive；Hygroscopic
Melt Point(°C)
172°C
Molecular Weight
203.620 g/mol
XLogP3
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
2
Exact Mass
203.035 Da
Monoisotopic Mass
203.035 Da
Topological Polar Surface Area
70.400 Ų
Heavy Atom Count
13
Formal Charge
0
Complexity
162.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
2
Citations of This Product
1.
Deng Hao-Hua, Yang Hui-Jing, Huang Kai-Yuan, Zheng Yi-Jing, Xu Ying-Ying, Peng Hua-Ping, Liu Yin-Huan, Chen Wei, Hong Guo-Lin.
(2022)
Antenna effect of pyridoxal phosphate on the fluorescence of mitoxantrone-silicon nanoparticles and its application in alkaline phosphatase assay. ANALYTICAL AND BIOANALYTICAL CHEMISTRY,
414
(17):
(4877-4884).
2.
Hao-Hua Deng, Kai-Yuan Huang, Quan-Hui Fang, Ya-Ping Lv, Shao-Bin He, Hua-Ping Peng, Xing-Hua Xia, Wei Chen.
(2020)
Schiff base and Lewis acid-base interaction-regulated aggregation/dispersion of gold nanoparticles for colorimetric recognition of rare-earth Sc3+ ions. SENSORS AND ACTUATORS B-CHEMICAL,
311
(127925).
3.
Q. Huang, Y. T. Chen, Y. W. Ren, Z. Y. Wang, Y. X. Zhu, Y. Zhang.
(2018)
A rapid and naked-eye visible rhodamine 6G-based chemosensor for sensitive detection of copper(II) ions in aqueous solution. Analytical Methods,
10
(47):
(5731-5737).
4.
Su Yao, Gongke Li, Yanqing Liu, Shoulian Wei, Hongwu Wang, Xiqing Huang, Zetao Luo.
(2018)
Electrochemical detection of pyridoxal using a sonoelectrochemical prepared highly-oxidized carbon nanosheets modified electrode. SENSORS AND ACTUATORS B-CHEMICAL,
274
(324).
5.
Qi Huang, Qingyou Zhang, Enze Wang, Yanmei Zhou, Han Qiao, Lanfang Pang, Fang Yu.
(2016)
A new “off–on” fluorescent probe for Al3+ in aqueous solution based on rhodamine B and its application to bioimaging. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,
152
(70).
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5 Citations
I2321834