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Pozelimab (anti-Complement C5) - Primary antibody, specific to C5, Human IgG4SP, INHIBITOR of Complement C5 inhibitor, INHIBITOR of Complement C5 inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab182838
Grouped product items
SKU Size
Availability
Price Qty
Ab182838-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab182838-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$519.90
Ab182838-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,399.90
Ab182838-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Pozelimab (anti-Complement C5) - Primary antibody, specific to C5, Human IgG4SP, INHIBITOR of Complement C5 inhibitor
Synonyms Anaphylatoxin C5a analog antibody | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 antibody | C5 antibody | C5a anaphylatoxin antibody | C5a antibody | C5b antibody | CO5_HUMAN antibody | Complement C5 alpha'' chain antibody | Complemen
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity C5
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Complement C5 inhibitor
Product Description

Pozelimab (anti-Complement C5) is a fully human IgG4 anti-C5 monoclonal antibody. Pozelimab (anti-Complement C5) binds to C5 and C5 variants with high affinity and blocks complement-mediated hemolysis. Pozelimab (anti-Complement C5) can be used for the research of complement-mediated diseases.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 144.78 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle
CAS 2096328-94-6

Associated Targets(Human)

C5 Tclin Complement C5 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Pozelimab (anti-Complement C5) (Ab182838) - ELISA
Immobilized Recombinant Human Complement C5 protein at 2.0 μg/mL can bind Pozelimab (anti-Complement C5) (Ab182838) with the EC ₅₀  of 2.302 ng/mL.

Pozelimab (anti-Complement C5) (Ab182838) - SEC
The purity of Pozelimab (anti-Complement C5) (Ab182838) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Alternative Products

Solution Calculators

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