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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab182838-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$109.90
|
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Ab182838-1mg
|
1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$519.90
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|
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Ab182838-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,399.90
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Ab182838-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,239.90
|
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Pozelimab (anti-Complement C5) - Primary antibody, specific to C5, Human IgG4SP, INHIBITOR of Complement C5 inhibitor |
|---|---|
| Synonyms | Anaphylatoxin C5a analog antibody | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 antibody | C5 antibody | C5a anaphylatoxin antibody | C5a antibody | C5b antibody | CO5_HUMAN antibody | Complement C5 alpha'' chain antibody | Complemen |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | C5 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Complement C5 inhibitor |
| Product Description |
Pozelimab (anti-Complement C5) is a fully human IgG4 anti-C5 monoclonal antibody. Pozelimab (anti-Complement C5) binds to C5 and C5 variants with high affinity and blocks complement-mediated hemolysis. Pozelimab (anti-Complement C5) can be used for the research of complement-mediated diseases. |
| Isotype | Human IgG4SP |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 144.78 kDa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle |
| CAS | 2096328-94-6 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Pozelimab (anti-Complement C5) (Ab182838) - ELISA
Immobilized Recombinant Human Complement C5 protein at 2.0 μg/mL can bind Pozelimab (anti-Complement C5) (Ab182838) with the EC
₅₀
of 2.302 ng/mL.
Pozelimab (anti-Complement C5) (Ab182838) - SEC
The purity of Pozelimab (anti-Complement C5) (Ab182838) is more than 95% verified by HPLC.
Starting at $89.90
Starting at $99.90
Starting at $109.90
Starting at $89.90
Starting at $89.90