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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab176427-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$59.90
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Ab176427-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$289.90
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Ab176427-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$749.90
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Ab176427-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,189.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Pepinemab (anti-SEMA4D) - Primary antibody, specific to SEMA4D, >95%, high purity, Human IgG4SP, INHIBITOR of Semaphorin-4D inhibitor |
|---|---|
| Synonyms | A8 antibody | BB 18 antibody | BB18 antibody | CD 100 antibody | CD100 antibody | CD100 antigen antibody | Coll 4 antibody | COLL4 antibody | Collapsin 4 antibody | Collapsin4 antibody | GR3 antibody | Leukocyte activation antigen CD100 antibody | M sema |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | SEMA4D |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Semaphorin-4D inhibitor |
| Product Description |
Pepinemab (anti-SEMA4D) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab (anti-SEMA4D) can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D. |
| Isotype | Human IgG4SP |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.88 kDa |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pepinemab (anti-SEMA4D) (Ab176427) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling SEMA4D with Pepinemab (anti-SEMA4D) (Ab176427) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
Pepinemab (anti-SEMA4D) (Ab176427) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling SEMA4D (red) with Pepinemab (anti-SEMA4D) (Ab176427) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
Pepinemab (anti-SEMA4D) (Ab176427) - SEC
The purity of Pepinemab (anti-SEMA4D) (Ab176427) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Nov 02, 2023 | Ab176427 | |
| Certificate of Analysis | Nov 02, 2023 | Ab176427 |