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Pepinemab (anti-SEMA4D) - Primary antibody, specific to SEMA4D, >95%, high purity, Human IgG4SP, INHIBITOR of Semaphorin-4D inhibitor, INHIBITOR of Semaphorin-4D inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab176427
Grouped product items
SKU Size
Availability
Price Qty
Ab176427-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab176427-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$289.90
Ab176427-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$749.90
Ab176427-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,189.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Pepinemab (anti-SEMA4D) - Primary antibody, specific to SEMA4D, >95%, high purity, Human IgG4SP, INHIBITOR of Semaphorin-4D inhibitor
Synonyms A8 antibody | BB 18 antibody | BB18 antibody | CD 100 antibody | CD100 antibody | CD100 antigen antibody | Coll 4 antibody | COLL4 antibody | Collapsin 4 antibody | Collapsin4 antibody | GR3 antibody | Leukocyte activation antigen CD100 antibody | M sema
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity SEMA4D
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Semaphorin-4D inhibitor
Product Description

Pepinemab (anti-SEMA4D) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab (anti-SEMA4D) can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 145.88 kDa
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

SEMA4D Tbio Semaphorin-4D (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Pepinemab (anti-SEMA4D) (Ab176427) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling SEMA4D with Pepinemab (anti-SEMA4D) (Ab176427) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Pepinemab (anti-SEMA4D) (Ab176427) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling SEMA4D (red) with Pepinemab (anti-SEMA4D) (Ab176427) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

Pepinemab (anti-SEMA4D) (Ab176427) - SEC
The purity of Pepinemab (anti-SEMA4D) (Ab176427) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1001511 Certificate of Analysis Nov 02, 2023 Ab176427
ZJ23F1001512 Certificate of Analysis Nov 02, 2023 Ab176427

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