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Oxotremorine sesquifumarate - 99%, high purity , CAS No.17360-35-9

    Grade & Purity:
  • ≥99%
  • Cas Number:  17360-35-9
  • Molecular Weight:  380.39 (anhydrous basis)
  • PubChem CID: 6436473
In stock
Item Number
O275069
Grouped product items
SKU Size
Availability
Price Qty
O275069-100mg
100mg
2
$96.90
O275069-500mg
500mg
1
$319.90
O275069-1g
1g
1
$499.90

Non-selective muscarinic receptor agonist

Basic Description

Synonyms 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone sesquifumarate
Specifications & Purity ≥99%
Biochemical and Physiological Mechanisms Non-selective muscarinic receptor agonist (pK i values are ~5 at M 1 , M 2 , M 3 and M 4 receptors). Restores neurogenesis. Active in vivo .Oxotremorine sesquifumarate salt is a muscarinic acetylcholine receptor agonist with preference for the M2 receptor
Storage Temp Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at +4°C. The product can be stored for up to 12 months.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Carboxylic acids and derivatives
Subclass Dicarboxylic acids and derivatives
Intermediate Tree Nodes Not available
Direct Parent Dicarboxylic acids and derivatives
Alternative Parents Unsaturated fatty acids  Pyrrolidine-2-ones  N-alkylpyrrolidines  Tertiary carboxylic acid amides  Trialkylamines  Lactams  Amino acids and derivatives  Carboxylic acids  Azacyclic compounds  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular Framework Not available
Substituents Dicarboxylic acid or derivatives - Pyrrolidone - 2-pyrrolidone - Unsaturated fatty acid - N-alkylpyrrolidine - Fatty acid - Fatty acyl - Pyrrolidine - Tertiary carboxylic acid amide - Lactam - Amino acid or derivatives - Tertiary amine - Tertiary aliphatic amine - Carboxamide group - Carboxylic acid - Azacycle - Organoheterocyclic compound - Organic oxygen compound - Amine - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Carbonyl group - Hydrocarbon derivative - Aliphatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups.
External Descriptors Not available

Associated Targets(Human)

BLM Tchem Bloom syndrome protein (4248 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name (E)-but-2-enedioic acid;1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidin-2-one
INCHI InChI=1S/2C12H18N2O.3C4H4O4/c2*15-12-6-5-11-14(12)10-4-3-9-13-7-1-2-8-13;3*5-3(6)1-2-4(7)8/h2*1-2,5-11H2;3*1-2H,(H,5,6)(H,7,8)/b;;3*2-1+
InChIKey WLYYOFJEBGHKEC-VQYXCCSOSA-N
Smiles C1CCN(C1)CC#CCN2CCCC2=O.C1CCN(C1)CC#CCN2CCCC2=O.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O
Isomeric SMILES C1CN(CC1)CC#CCN2C(=O)CCC2.C1CN(CC1)CC#CCN2C(=O)CCC2.C(=C/C(=O)O)\C(=O)O.C(=C/C(=O)O)\C(=O)O.C(=C/C(=O)O)\C(=O)O
PubChem CID 6436473
Molecular Weight 380.39 (anhydrous basis)

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number Certificate Type Date Item
B2427408 Certificate of Analysis May 15, 2025 O275069
B2427411 Certificate of Analysis May 15, 2025 O275069
B2427410 Certificate of Analysis Dec 09, 2024 O275069
B2427397 Certificate of Analysis Dec 09, 2024 O275069
B2427409 Certificate of Analysis Dec 09, 2024 O275069

Chemical and Physical Properties

Solubility Soluble in DMSO to 100 mM, in ethanol to 100 mM, in water to 25 mM and in PBS to 25 mM
Molecular Weight 760.800 g/mol
XLogP3
Hydrogen Bond Donor Count 6
Hydrogen Bond Acceptor Count 16
Rotatable Bond Count 10
Exact Mass 760.317 Da
Monoisotopic Mass 760.317 Da
Topological Polar Surface Area 271.000 Ų
Heavy Atom Count 54
Formal Charge 0
Complexity 412.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 3
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 3
Covalently-Bonded Unit Count 5

Solution Calculators

Reviews

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