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OS2966 (anti-ITGB1) - Primary antibody, specific to ITGB1, >95%, high purity, Human IgG1

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OS2966 (anti-ITGB1) - Primary antibody, specific to ITGB1, >95%, high purity, Human IgG1

Grade & Purity:

≥95%(SDS-PAGE&SEC-HPLC)
See COA

Application:

Animal Model
ELISA
Flow Cytometry
Functional Assay

Host species: Human
Reactive species: Human
Isotype: Human IgG1
Conjugation: Unconjugated

In stock

Item Number

Ab177919

Grouped product items
SKU	Size	Availability	Price	Qty
Ab177919-100μg	100μg	10	$109.90
Ab177919-1mg	1mg	4	$519.90
Ab177919-5mg	5mg	1	$1,399.90
Ab177919-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,239.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series

Click to view target information: ITGB1

Accession#:P05556 (3) Gene ID:3688 (3) Integrin beta 1 (3) ITGB1 (4)

Basic Description

Product Name	OS2966 (anti-ITGB1) - Primary antibody, specific to ITGB1, >95%, high purity, Human IgG1
Synonyms	Fibronectin receptor subunit beta \| Glycoprotein IIa \| GPIIA \| VLA-4 subunit beta
Specifications & Purity	Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species	Human
Specificity	ITGB1
Conjugation	Unconjugated
Grade	Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description	OS2966 (anti-ITGB1) is a humanized monoclonal antibody directed against the human integrin receptor beta-1 subunit (CD29), with potential antineoplastic activity.

Product Properties

Isotype	Human IgG1
Light Chain Type	kappa
SDS-PAGE	26.3 kDa (Light Chain) & 51.5 kDa (Heavy Chain), under reducing conditions; 176.1 kDa, under non-reducing conditions.
Purification Method	Protein A purified
Purity	>95%
Shape	Liquid
Concentration	See COA
Storage Temp	Store at -80°C,Avoid repeated freezing and thawing
Shipped In	Ice chest + Ice pads
Stability And Storage	Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

ITGB1 Tclin Integrin beta-1 (0 Activities)

Discover Target: ITGB1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ITGB1 Tclin Fibronectin receptor beta (8 Activities)

Discover Target: ITGB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ITGB1 Tclin Integrin alpha-4/beta-1 (2269 Activities)

Discover Target: ITGB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ITGB1 Tclin Integrin alpha-5/beta-1 (686 Activities)

Discover Target: ITGB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ITGB1 Tclin Integrin alpha-V/beta-1 (222 Activities)

Discover Target: ITGB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ITGB1 Tclin Integrin alpha2/beta1 (69 Activities)

Discover Target: ITGB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ITGB1 Tclin Integrin alpha1/beta1 complex (6 Activities)

Discover Target: ITGB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ITGB1 Tclin Integrin alpha-10/Integrin beta-1 (1 Activities)

Discover Target: ITGB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ITGB1 Tclin ITGA6-ITGB1 complex (1 Activities)

Discover Target: ITGB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Images

Flow Cytometry: OS2966 (anti-ITGB1) (Ab177919)

OS2966 (anti-ITGB1) (Ab177919) - Flow Cytometry
Flow Cytometry analysis of U-2 OS cells labelling ITGB1 (red) with OS2966 (anti-ITGB1) (Ab177919). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: OS2966 (anti-ITGB1) (Ab177919)

OS2966 (anti-ITGB1) (Ab177919) - Flow Cytometry
Flow Cytometry analysis of Hela cells labelling ITGB1 (red) with OS2966 (anti-ITGB1) (Ab177919). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: OS2966 (anti-ITGB1) (Ab177919)

OS2966 (anti-ITGB1) (Ab177919) - Flow Cytometry
Flow Cytometry analysis of A431 cells labelling ITGB1 (red) with OS2966 (anti-ITGB1) (Ab177919). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

SEC: OS2966 (anti-ITGB1) (Ab177919)

OS2966 (anti-ITGB1) (Ab177919) - SEC
The purity of OS2966 (anti-ITGB1) (Ab177919) is more than 95% verified by HPLC.

Flow Cytometry: OS2966 (anti-ITGB1) (Ab177919)

OS2966 (anti-ITGB1) (Ab177919) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling ITGB1 with OS2966 (anti-ITGB1) (Ab177919) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Flow Cytometry: OS2966 (anti-ITGB1) (Ab177919)

OS2966 (anti-ITGB1) (Ab177919) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling ITGB1 (red) with OS2966 (anti-ITGB1) (Ab177919) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

ELISA: OS2966 (anti-ITGB1) (Ab177919)

OS2966 (anti-ITGB1) (Ab177919) - ELISA
Immobilized Recombinant Human Integrin beta 1 Protein (rp186545) at 1.0 μg/mL can bind OS2966 (anti-ITGB1) (Ab177919) with the EC₅₀ of 36.5 ng/mL.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Date	Item
ZJ24F0404072	Certificate of Analysis	Apr 02, 2024	Ab177919
ZJ24F0404071	Certificate of Analysis	Apr 02, 2024	Ab177919
ZJ24F0404070	Certificate of Analysis	Apr 02, 2024	Ab177919

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