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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170497-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$69.90
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Ab170497-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$327.90
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Ab170497-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$897.90
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Ab170497-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,407.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Nadunolimab (anti-IL-1 RAcP) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IL1RAP, >95%, high purity, Human IgG1 |
|---|---|
| Synonyms | C3orf13IL-1RAcPIL1R3Interleukin-1 receptor 3 | FLJ37788 | IL-1 R3 | IL-1 RAcP | IL-1 receptor accessory protein | IL-1R3 | IL-1R-3 | IL1RAcP | IL-1RAcP | IL1RAP | interleukin 1 receptor accessory protein | interleukin-1 receptor accessory protein beta | i |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | IL1RAP |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Nadunolimab is a human monoclonal IgG1 antibody targeting IL1RAP. Nadunolimab blocks IL-1α and IL-1β signaling and triggering antibody-dependent cellular cytotoxicity. Nadunolimab can be used in research of cancer. |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG1 |
| Light Chain Type | kappa |
| SDS-PAGE | 27.7 kDa (Light Chain) & 52.7 kDa (Heavy Chain), under reducing conditions; 178.0 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2171061-85-9 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Nadunolimab (anti-IL-1 RAcP) (Ab170497) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling IL-1 RAcP (red) with Nadunolimab (anti-IL-1 RAcP) (Ab170497). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Nadunolimab (anti-IL-1 RAcP) (Ab170497) - SEC
The purity of Nadunolimab (anti-IL-1 RAcP) (Ab170497) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Oct 10, 2023 | Ab170497 | |
| Certificate of Analysis | Oct 10, 2023 | Ab170497 |
Starting at $69.90