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Nadecnemab (anti-GFRA3) - Primary antibody, specific to GFRA3, >95%, high purity, Human IgG4SP

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab177932
Grouped product items
SKU Size
Availability
Price Qty
Ab177932-100μg
100μg
10
$109.90
Ab177932-1mg
1mg
4
$509.90
Ab177932-5mg
5mg
1
$1,259.90
Ab177932-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,989.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Nadecnemab (anti-GFRA3) - Primary antibody, specific to GFRA3, >95%, high purity, Human IgG4SP
Synonyms GDNF receptor alpha-3 | GDNFR-alpha-3 | GFR-alpha-3
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity GFRA3
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Nadecnemab (anti-GFRA3) is an IgG4κ antibody targeting to GFRA3, glial cell derived neurotrophic factor family receptor alpha 3. Nadecnemab (anti-GFRA3) can be used for research of osteoarthritis of the knee/pain[1].

Product Properties

Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 27.0 kDa (Light Chain) & 52.8 kDa (Heavy Chain), under reducing conditions; 181.1 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2377679-19-9

Associated Targets(Human)

GFRA3 Tbio GDNF family receptor alpha-3 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Nadecnemab (anti-GFRA3) (Ab177932) - ELISA
Immobilized Hu-GFRA3-His at 2 μg/mL can bind Nadecnemab (anti-GFRA3) (Ab177932) with the EC₅₀ of 11.80 ng/mL.

Nadecnemab (anti-GFRA3) (Ab177932) - SEC
The purity of Nadecnemab (anti-GFRA3) (Ab177932) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303030 Certificate of Analysis Mar 08, 2024 Ab177932
ZJ24F0303029 Certificate of Analysis Mar 08, 2024 Ab177932
ZJ24F0303028 Certificate of Analysis Mar 08, 2024 Ab177932

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