Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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M131144-100mg
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100mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$94.90
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M131144-500mg
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500mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$331.90
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M131144-1g
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1g |
1
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$597.90
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Fluorescent chloride ion indicator
| Synonyms | FT-0629283 | Quinolinium, 1-(2-ethoxy-2-oxoethyl)-6-methoxy-, bromide (1:1) | SB73053 | 1-(2-Ethoxy-2-oxoethyl)-6-methoxyquinolin-1-ium bromide | 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide | SCHEMBL223614 | MQAE | Quinolinium,1-(2-ethoxy-2-oxoe |
|---|---|
| Specifications & Purity | for fluorescence analysis, ≥97% |
| Biochemical and Physiological Mechanisms | Fluorescent chloride ion indicator. Quenches via collision with chloride. Measures chloride transport in liposome membranes. |
| Storage Temp | Store at 2-8°C,Protected from light,Argon charged |
| Shipped In |
Wet ice This product requires cold chain shipping. Ground and other economy services are not available. |
| Grade | for fluorescence analysis |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
MQAE is a fluorescent chloride ion indicator that is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells. MQAE is a fluorescent indicator that is quenched via collision with chloride. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Intermediate Tree Nodes | Amino acids and derivatives - Alpha amino acids and derivatives |
| Direct Parent | Alpha amino acid esters |
| Alternative Parents | Quinolines and derivatives Anisoles Alkyl aryl ethers Pyridinium derivatives Heteroaromatic compounds Carboxylic acid esters Monocarboxylic acids and derivatives Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Organic bromide salts Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Alpha-amino acid ester - Quinoline - Anisole - Alkyl aryl ether - Pyridine - Pyridinium - Benzenoid - Heteroaromatic compound - Carboxylic acid ester - Organoheterocyclic compound - Azacycle - Monocarboxylic acid or derivatives - Ether - Organic salt - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Carbonyl group - Organopnictogen compound - Organic oxygen compound - Organic bromide salt - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as alpha amino acid esters. These are ester derivatives of alpha amino acids. |
| External Descriptors | Not available |
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| IUPAC Name | ethyl 2-(6-methoxyquinolin-1-ium-1-yl)acetate;bromide |
|---|---|
| INCHI | InChI=1S/C14H16NO3.BrH/c1-3-18-14(16)10-15-8-4-5-11-9-12(17-2)6-7-13(11)15;/h4-9H,3,10H2,1-2H3;1H/q+1;/p-1 |
| InChIKey | DSLLHVISNOIYHR-UHFFFAOYSA-M |
| Smiles | CCOC(=O)C[N+]1=CC=CC2=C1C=CC(=C2)OC.[Br-] |
| Isomeric SMILES | CCOC(=O)C[N+]1=CC=CC2=C1C=CC(=C2)OC.[Br-] |
| WGK Germany | 3 |
| Molecular Weight | 326.186 |
| Reaxy-Rn | 24187730 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24187730&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 02, 2024 | M131144 | |
| Certificate of Analysis | Apr 02, 2024 | M131144 | |
| Certificate of Analysis | Apr 02, 2024 | M131144 | |
| Certificate of Analysis | Aug 07, 2023 | M131144 | |
| Certificate of Analysis | Aug 07, 2023 | M131144 |
| Sensitivity | light sensitive.Hygroscopic |
|---|---|
| Molecular Weight | 326.190 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 5 |
| Exact Mass | 325.031 Da |
| Monoisotopic Mass | 325.031 Da |
| Topological Polar Surface Area | 39.400 Ų |
| Heavy Atom Count | 19 |
| Formal Charge | 0 |
| Complexity | 282.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
| 1. Sun Weijia, Li Yuheng, Li Jianwei, Tan Yingjun, Yuan Xinxin, Meng Haoye, Ye Jianting, Zhong Guohui, Jin XiaoYan, Liu Zizhong, Du Ruikai, Xing Wenjuan, Zhao Dingsheng, Song Jinping, Li Youyou, Pan Junjie, Zhao Yunzhang, Li Qi, Wang Aiyuan, Ling Shukuan, Dai Rongji, Li Yingxian. (2023) Mechanical stimulation controls osteoclast function through the regulation of Ca2+-activated Cl− channel Anoctamin 1. Communications Biology, 6 (1): (1-13). |
| 2. Xi-Hui Yu, Xiong-Jie Cai, Xiao-Qiao Hong, Kin Yip Tam, Kun Zhang, Wen-Hua Chen. (2019) Synthesis and biological evaluation of aza-crown ether–squaramide conjugates as anion/cation symporters. Future Medicinal Chemistry, 11 (10): |
| 3. Xi-Hui Yu,Xiao-Qiao Hong,Wen-Hua Chen. (2019-01-30) Fluorinated bisbenzimidazoles: a new class of drug-like anion transporters with chloride-mediated, cell apoptosis-inducing activity.. Organic & biomolecular chemistry, 17 ((6)): (1558-1571). |
| 4. Na Wang, Anqi Yang, Xiong Tian, Jiaqi Liao, Zhenyu Yang, Yixiao Pan, Yiqing Guo, Sailing He. (2024) Label-free analysis of the β-hydroxybutyricacid drug on mitochondrial redox states repairment in type 2 diabetic mice by resonance raman scattering. BIOMEDICINE & PHARMACOTHERAPY, 172 (116320). |