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MQAE [1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide] - ≥97.0%,For fluorescence analysis, high purity , CAS No.162558-52-3

In stock
Item Number
M131144
Grouped product items
SKU Size
Availability
Price Qty
M131144-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$94.90
M131144-500mg
500mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$331.90
M131144-1g
1g
1
$597.90

Fluorescent chloride ion indicator

View related series
Fluorescent Dye (372)

Basic Description

Synonyms FT-0629283 | Quinolinium, 1-(2-ethoxy-2-oxoethyl)-6-methoxy-, bromide (1:1) | SB73053 | 1-(2-Ethoxy-2-oxoethyl)-6-methoxyquinolin-1-ium bromide | 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide | SCHEMBL223614 | MQAE | Quinolinium,1-(2-ethoxy-2-oxoe
Specifications & Purity for fluorescence analysis, ≥97%
Biochemical and Physiological Mechanisms Fluorescent chloride ion indicator. Quenches via collision with chloride. Measures chloride transport in liposome membranes.
Storage Temp Store at 2-8°C,Protected from light,Argon charged
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade for fluorescence analysis
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

MQAE is a fluorescent chloride ion indicator that is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells. MQAE is a fluorescent indicator that is quenched via collision with chloride.
1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide, a fluorescent chloride indicator dye, may be used to measure intracellular and extracellular chloride concentrations.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Carboxylic acids and derivatives
Subclass Amino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct Parent Alpha amino acid esters
Alternative Parents Quinolines and derivatives  Anisoles  Alkyl aryl ethers  Pyridinium derivatives  Heteroaromatic compounds  Carboxylic acid esters  Monocarboxylic acids and derivatives  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Organic bromide salts  Hydrocarbon derivatives  Carbonyl compounds  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Alpha-amino acid ester - Quinoline - Anisole - Alkyl aryl ether - Pyridine - Pyridinium - Benzenoid - Heteroaromatic compound - Carboxylic acid ester - Organoheterocyclic compound - Azacycle - Monocarboxylic acid or derivatives - Ether - Organic salt - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Carbonyl group - Organopnictogen compound - Organic oxygen compound - Organic bromide salt - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as alpha amino acid esters. These are ester derivatives of alpha amino acids.
External Descriptors Not available

Names and Identifiers

IUPAC Name ethyl 2-(6-methoxyquinolin-1-ium-1-yl)acetate;bromide
INCHI InChI=1S/C14H16NO3.BrH/c1-3-18-14(16)10-15-8-4-5-11-9-12(17-2)6-7-13(11)15;/h4-9H,3,10H2,1-2H3;1H/q+1;/p-1
InChIKey DSLLHVISNOIYHR-UHFFFAOYSA-M
Smiles CCOC(=O)C[N+]1=CC=CC2=C1C=CC(=C2)OC.[Br-]
Isomeric SMILES CCOC(=O)C[N+]1=CC=CC2=C1C=CC(=C2)OC.[Br-]
WGK Germany 3
Molecular Weight 326.186
Reaxy-Rn 24187730
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24187730&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number Certificate Type Date Item
F2220237 Certificate of Analysis Apr 02, 2024 M131144
F2220238 Certificate of Analysis Apr 02, 2024 M131144
F2220239 Certificate of Analysis Apr 02, 2024 M131144
K2104175 Certificate of Analysis Aug 07, 2023 M131144
K2104115 Certificate of Analysis Aug 07, 2023 M131144

Chemical and Physical Properties

Sensitivity light sensitive.Hygroscopic
Molecular Weight 326.190 g/mol
XLogP3
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 5
Exact Mass 325.031 Da
Monoisotopic Mass 325.031 Da
Topological Polar Surface Area 39.400 Ų
Heavy Atom Count 19
Formal Charge 0
Complexity 282.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 2

Citations of This Product

1. Sun Weijia, Li Yuheng, Li Jianwei, Tan Yingjun, Yuan Xinxin, Meng Haoye, Ye Jianting, Zhong Guohui, Jin XiaoYan, Liu Zizhong, Du Ruikai, Xing Wenjuan, Zhao Dingsheng, Song Jinping, Li Youyou, Pan Junjie, Zhao Yunzhang, Li Qi, Wang Aiyuan, Ling Shukuan, Dai Rongji, Li Yingxian.  (2023)  Mechanical stimulation controls osteoclast function through the regulation of Ca2+-activated Cl− channel Anoctamin 1.  Communications Biology,  (1): (1-13). 
2. Xi-Hui Yu, Xiong-Jie Cai, Xiao-Qiao Hong, Kin Yip Tam, Kun Zhang, Wen-Hua Chen.  (2019)  Synthesis and biological evaluation of aza-crown ether–squaramide conjugates as anion/cation symporters.  Future Medicinal Chemistry,  11  (10):  
3. Xi-Hui Yu,Xiao-Qiao Hong,Wen-Hua Chen.  (2019-01-30)  Fluorinated bisbenzimidazoles: a new class of drug-like anion transporters with chloride-mediated, cell apoptosis-inducing activity..  Organic & biomolecular chemistry,  17  ((6)): (1558-1571). 
4. Na Wang, Anqi Yang, Xiong Tian, Jiaqi Liao, Zhenyu Yang, Yixiao Pan, Yiqing Guo, Sailing He.  (2024)  Label-free analysis of the β-hydroxybutyricacid drug on mitochondrial redox states repairment in type 2 diabetic mice by resonance raman scattering.  BIOMEDICINE & PHARMACOTHERAPY,  172  (116320). 

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