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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab183002-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab183002-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$519.90
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Ab183002-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,299.90
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Ab183002-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,079.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Mipasetamab (anti-AXL) - Primary antibody, specific to AXL, Human IgG1 |
|---|---|
| Synonyms | Adhesion related kinase antibody | AI323647 antibody | Ark antibody | Axl antibody | AXL oncogene antibody | AXL receptor tyrosine kinase antibody | AXL transforming gene antibody | AXL transforming sequence/gene antibody | EC 2.7.10.1 antibody | JTK11 an |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | AXL |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Mipasetamab (anti-AXL) is an IgG1κ antibody targeting to AXL, a tyrosine kinase receptor and an TAM Receptor. Mipasetamab (anti-AXL) involves in synthesis of ADCT-601 (Mipasetamab uzoptirine), an AXL-targeted antibody-drug conjugate (ADC). ADCT-601 has anti-tumor activity.
|
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.5 kDa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2361055-48-1 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Mipasetamab (anti-AXL) (Ab183002) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling AXL (red) with Mipasetamab (anti-AXL) (Ab183002). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Mipasetamab (anti-AXL) (Ab183002) - Flow Cytometry
Flow Cytometry analysis of A431 cells labelling AXL (red) with Mipasetamab (anti-AXL) (Ab183002). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Mipasetamab (anti-AXL) (Ab183002) - ELISA
Immobilized Recombinant Human AXL protein (rp183600) at 1.0 μg/mL can bind Mipasetamab (anti-AXL) (Ab183002) with the EC
₅₀
of 24.0 ng/mL.
Mipasetamab (anti-AXL) (Ab183002) - SEC
The purity of Mipasetamab (anti-AXL) (Ab183002) is more than 95% verified by HPLC.
Starting at $59.90
Starting at $109.90
Starting at $69.90