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Mipasetamab (anti-AXL) - Primary antibody, specific to AXL, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab183002
Grouped product items
SKU Size
Availability
Price Qty
Ab183002-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab183002-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$519.90
Ab183002-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,299.90
Ab183002-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,079.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Mipasetamab (anti-AXL) - Primary antibody, specific to AXL, Human IgG1
Synonyms Adhesion related kinase antibody | AI323647 antibody | Ark antibody | Axl antibody | AXL oncogene antibody | AXL receptor tyrosine kinase antibody | AXL transforming gene antibody | AXL transforming sequence/gene antibody | EC 2.7.10.1 antibody | JTK11 an
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity AXL
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Mipasetamab (anti-AXL) is an IgG1κ antibody targeting to AXL, a tyrosine kinase receptor and an TAM Receptor. Mipasetamab (anti-AXL) involves in synthesis of ADCT-601 (Mipasetamab uzoptirine), an AXL-targeted antibody-drug conjugate (ADC). ADCT-601 has anti-tumor activity.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 145.5 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2361055-48-1

Associated Targets(Human)

AXL Tchem Tyrosine-protein kinase receptor UFO (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
AXL Tchem Tyrosine-protein kinase receptor UFO (3469 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AXL Tchem TEL/AXL (11 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Mipasetamab (anti-AXL) (Ab183002) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling AXL (red) with Mipasetamab (anti-AXL) (Ab183002). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Mipasetamab (anti-AXL) (Ab183002) - Flow Cytometry
Flow Cytometry analysis of A431 cells labelling AXL (red) with Mipasetamab (anti-AXL) (Ab183002). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Mipasetamab (anti-AXL) (Ab183002) - ELISA
Immobilized Recombinant Human AXL protein (rp183600) at 1.0 μg/mL can bind Mipasetamab (anti-AXL) (Ab183002) with the EC ₅₀  of 24.0 ng/mL.

Mipasetamab (anti-AXL) (Ab183002) - SEC
The purity of Mipasetamab (anti-AXL) (Ab183002) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

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