Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab182821-100μg
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100μg |
10
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$69.90
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Ab182821-1mg
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1mg |
4
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$349.90
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Ab182821-5mg
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5mg |
1
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$899.90
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Ab182821-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,439.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Melrilimab (anti-IL-33R) - Primary antibody, specific to IL1RL1, Human IgG2SA |
|---|---|
| Synonyms | DER-4 antibody | DER4 antibody | FIT 1 antibody | Growth stimulation expressed antibody | homolog of mouse growth stimulation-expressed antibody | Il1rl1 antibody | IL33R antibody | ILRL1_HUMAN antibody | Interleukin 1 receptor like 1 antibody | interleuk |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | IL1RL1 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Melrilimab (anti-IL-33R) is an IgG2-kappa anti-IL1RL1/ST2/IL33R/DER4/FIT-1 monoclonal antibody. Melrilimab (anti-IL-33R) can be used for the research of asthma. |
| Isotype | Human IgG2SA |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.6 kDa (Light Chain) & 51.1 kDa (Heavy Chain), under reducing conditions; 194.8 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2222865-46-3 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Melrilimab (anti-IL-33R) (Ab182821) - ELISA
Immobilized Human ST2/IL-33R Protein (rp169684) at 1.0 μg/mL can bind Melrilimab (anti-IL-33R) (Ab182821) with the EC₅₀ of 30.05 ng/mL.
Melrilimab (anti-IL-33R) (Ab182821) - SEC
The purity of Melrilimab (anti-IL-33R) (Ab182821) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | May 06, 2024 | Ab182821 | |
| Certificate of Analysis | May 06, 2024 | Ab182821 | |
| Certificate of Analysis | May 06, 2024 | Ab182821 |
Starting at $69.90
Starting at $69.90
Starting at $79.90