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12 Items

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  1. TAK 044, Antagonist of ET A receptor;Antagonist of ET B receptor
    IUPAC Name:  2-[(2R,5S,8S,11S,14S,17R)-8-(carboxymethyl)-17-(1H-indol-3-ylmethyl)-14-(2-methylpropyl)-3,6,9,12,15,18-hexaoxo-5-[2-oxo-2-(4-phenylpiperidin-1-yl)ethshow more
    SMILES:  CC(C[C@@H]1NC(=O)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](NC1=O)Cc1c[nH]c2c1cccc2)CC(=O)O)CC(=O)N1CCC(CC1)c1ccccc1)c1cccs1)C
    InChIKey: UOZMDLYHZJQAOO-YHIUFLQMSA-N
    InChI:  InChI=1S/C46H54N8O11S/c1-25(2)19-31-41(60)48-32(20-28-24-47-30-12-7-6-11-29(28)30)42(61)50-34(22-38(56)57)44(63)49-33(21-37(55)54-16-14-27(15-17-54)26show more
    Synonyms: TAK-044 | TAK044
  2. [¹²⁵I]ET-2 (human), Agonist of ET A receptor
    SMILES:  CC[C@H](C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@show more
    InChIKey: XBZLMXIYDPWXEV-IYRKOGFYSA-N
    InChI:  InChI=1S/C115H164N26O32S4/c1-11-59(9)93(113(170)132-82(115(172)173)41-64-46-120-71-27-19-17-25-68(64)71)141-114(171)94(60(10)12-2)140-105(162)81(44-91show more
    Synonyms: [¹²⁵I]endothelin-2
  3. [¹²⁵I]ET-1 (human, mouse, rat), Agonist of ET A receptor;Agonist of ET B receptor
    SMILES:  CC[C@H](C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@show more
    InChIKey: IWBLZZSEUHZWPR-ZTNLKOGPSA-N
    InChI:  InChI=1S/C109H163N25O32S5/c1-12-56(9)87(107(163)125-76(109(165)166)39-60-43-113-65-24-18-17-23-63(60)65)134-108(164)88(57(10)13-2)133-99(155)75(42-85(show more
    Synonyms: [¹²⁵I]endothelin-1
  4. [³H]BQ123, Antagonist of ET A receptor
    SMILES:  CC(C[C@@H]1NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](NC1=O)Cc1c[nH]c2c1cccc2)C(C(=O)O)[3H])C(C)C)C
    InChIKey: VYCMAAOURFJIHD-HCGDBENESA-N
    InChI:  InChI=1S/C31H42N6O7/c1-16(2)12-21-27(40)33-22(13-18-15-32-20-9-6-5-8-19(18)20)28(41)35-23(14-25(38)39)31(44)37-11-7-10-24(37)29(42)36-26(17(3)4)30(43)show more
    Synonyms: [³H]-BQ123;[³H]cyc(DTrp-DAsp-Pro-DVal-Leu
  5. [¹²⁵I]PD151242, Antagonist of ET A receptor
    IUPAC Name:  (2R)-2-[[(2R)-2-[[(2S)-2-(azepane-1-carbonylamino)-4-methylpentanoyl]amino]-3-(1-methylindol-3-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
    SMILES:  CC(C[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)O)Cc1ccc(cc1)O)Cc1cn(c2c1cccc2)C)NC(=O)N1CCCCCC1)C
    InChIKey: JVILFANCFWZBFU-ZGIBFIJWSA-N
    InChI:  InChI=1S/C34H45N5O6/c1-22(2)18-27(37-34(45)39-16-8-4-5-9-17-39)31(41)35-28(20-24-21-38(3)30-11-7-6-10-26(24)30)32(42)36-29(33(43)44)19-23-12-14-25(40)show more
    Synonyms: AKOS025394398 | J-009206 | D-Tyrosine, N-(N-(N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl)-1-methyl-D-tryptophyl)-...
  6. pegfilgrastim, Agonist of Granulocyte colony-stimulating factor receptor
    Cas Number: 208265-92-3        EC Number: 274-613-9, 641-363-0
    IUPAC Name:  1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;methanesulfonic acid
    SMILES:  CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O.CS(=O)(=O)O
    InChIKey: HQQSBEDKMRHYME-UHFFFAOYSA-N
    InChI:  InChI=1S/C17H20FN3O3.CH4O3S/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21;1-5(2,3)4/h8-10H,3-7H2,1-2H3,(H,23,24);1H3,(H,2,3show more
    Synonyms: 1589 mR.B. | STL445507 | (3-hydroxypropyl)carbamic acid tert-butyl ester | 1-Ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1...
  7. sarafotoxin S6b, Agonist of ET A receptor
    Cas Number: 116303-65-2        Compound CID:  71308726
    SMILES:  NCCCC[C@@H]1NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CC(=O)O)CCSC)[C@H](O)C)show more
    InChIKey: ZHRYDGYRZIWZPS-RAALVGGVSA-N
    InChI:  InChI=1S/C110H159N27O34S5/c1-9-55(6)88(108(168)130-77(110(170)171)40-59-45-116-64-22-14-13-21-62(59)64)136-107(167)87(54(4)5)135-102(162)76(44-86(148)show more
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